Hypoglycemia as a Result of Propranolol During Treatment of Infantile Hemangioma: A Case Report

被引:52
作者
Breur, Johannes M. P. J. [1 ]
de Graaf, Marlies [2 ]
Breugem, Corstiaan C. [3 ]
Pasmans, Suzanne G. M. A. [2 ]
机构
[1] Wilhelmina Childrens Hosp, Univ Med Ctr Utrecht, Ctr Congenital Vasc Anomalies Utrecht, Dept Pediat Cardiol, NL-3584 EA Utrecht, Netherlands
[2] Wilhelmina Childrens Hosp, Univ Med Ctr Utrecht, Ctr Congenital Vasc Anomalies Utrecht, Dept Pediat Dermatol & Allergol, NL-3584 EA Utrecht, Netherlands
[3] Wilhelmina Childrens Hosp, Univ Med Ctr Utrecht, Ctr Congenital Vasc Anomalies Utrecht, Dept Pediat Plast Surg, NL-3584 EA Utrecht, Netherlands
关键词
D O I
10.1111/j.1525-1470.2010.01224.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Propranolol is a new and promising treatment for hemangiomas of infancy. We report of a patient in whom steroid maintenance therapy is successfully tapered after introduction of propranolol. This patient, however, developed symptomatic hypoglycemic events presumably because of a concurrent deficiency of epinephrine and cortisol as a direct result of both beta-blockage by propranolol and adrenal insufficiency as a result of prednisone use. Extreme care should be taken in patients treated with both propranolol and prednisone as they are at increased risk of hypoglycemia.
引用
收藏
页码:169 / 171
页数:3
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