Concentric electrodes improve microfluidic droplet sorting

被引：39

作者：

Clark, Iain C. ^{[1
]}

Thakur, Rohan ^{[1
]}

Abate, Adam R. ^{[1
]}

机构：

[1] Univ Calif San Francisco, Dept Bioengn & Therapeut Sci, San Francisco, CA 94143 USA

来源：

LAB ON A CHIP | 2018年 / 18卷 / 05期

关键词：

DEVICES;

D O I：

10.1039/c7lc01242j

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Microfluidic droplet sorting allows selection of subpopulations of cells, nucleic acids, and biomolecules with soluble assays. Dielectrophoresis is widely used for sorting because it generates strong forces on droplets, actuates rapidly, and is easy to integrate into microfluidic chips. However, existing device designs apply a short force, limiting the deflection of droplets, and therefore the speed and reliability of sorting. We describe a concentric design that applies a long force, allowing large deflections and increased reliability. We demonstrate the utility of this design by sorting polydisperse emulsions, which are typically difficult to sort with high purity. © 2018 The Royal Society of Chemistry.

引用

页码：710 / 713

页数：4

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