Hyperuricaemia in patients with type 2 diabetes in a tertiary healthcare centre in sub-Saharan Africa: prevalence and determinants

被引：5

作者：

Choukem, Simeon-Pierre ^{[1
,2
,3
]}

Mengue, Juliette-Amelie ^{[4
,5
]}

Doualla, Marie-Solange ^{[2
]}

Donfack, Olivier-Tresor ^{[6
]}

Beyiha, Gerard ^{[7
]}

Luma, Henry N. ^{[2
]}

机构：

[1] Hlth & Human Dev 2HD Res Grp, Med, Douala, Cameroon

[2] Douala Gen Hosp, Dept Internal Med, Med, Douala, Douala, Cameroon

[3] Univ Buea, Dept Internal Med & Paediat, Med, Fac Hlth Sci, Buea, Cameroon

[4] Hlth & Human Dev 2HD Res Grp, Douala, Cameroon

[5] Univ Douala, Fac Med & Pharmaceut Sci, Douala, Cameroon

[6] Univ Yaounde, Ctr Biotechnol, Lab Mol Med & Metab, Yaounde, Cameroon

[7] Univ Douala, Fac Med & Pharmaceut Sci, Med, Douala, Cameroon

来源：

TROPICAL DOCTOR | 2016年 / 46卷 / 04期

关键词：

Hyperuricaemia; type 2 diabetes mellitus; prevalence; determinants; Cameroon; SERUM URIC-ACID; CARDIOVASCULAR RISK-FACTORS; METABOLIC SYNDROME; DISEASE; ACTIVATION; MELLITUS;

D O I：

10.1177/0049475515626030

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Hyperuricaemia in type 2 diabetes mellitus (T2DM) has been less well investigated in sub-Saharan Africans. Our study of 438 patients found that alcohol intake, body mass index 25kg/m(2), hydrochlorothiazide use, statin use, diabetic retinopathy and glomerular filtration rate <60mL/min/1.73m(2) were independently positively associated with hyperuricaemia; whereas smoking reduced this risk. Hyperuricaemia is strongly associated with some modifiable factors, diabetic complications and certain drugs. Our results suggest that further studies should evaluate the potential cost-benefit of screening for hyperuricaemia in type 2 diabetes.

引用

页码：216 / 221

页数：6

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