Reactions with hydrazonoyl halides -: 59:: Synthesis and antimicrobial activity of 2,3-dihydro-1,3,4-thiadiazole, triazolino[4,3-a]pyrimidine, and pyrimido[1,2-b][1,2,4,5]tetrazin-6-one containing benzofuran moiety

被引:11
作者
Abdelhamid, Abdou O. [1 ]
Mohamed, Mahmoud A. [2 ]
Zaki, Yasser H. [3 ]
机构
[1] Cairo Univ, Dept Chem, Fac Sci, Giza 12613, Egypt
[2] Beni Suef Univ, Fac Ind Educ, Dept Text, Bani Suwayf, Egypt
[3] Beni Suef Univ, Dept Chem, Fac Sci, Bani Suwayf, Egypt
关键词
2,3-dihydro-1,3,4-thiadiazole; hydrazonoyl bromide; pyrimido[1,2-b][1,2,4,5] tetrazin-6-one; triazolino[4,3-a]pyrimidine;
D O I
10.1080/10426500701734265
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
2,3-Dihydro-1,3,4-thiadiazole, triazolino[4,3-a]pyrimidine and pyrimido[1,2-b][1,2,4,5]tetrazin-6-one containing benzofuran Moiety were synthesized from C-benzofuran-2-yl-N-phenylhydrazonoyl bromides, and the appropriate alkyl arylidenehydrazinecabodithioates and pyrimidine-2-thione and N-aminopyrimidine-2-thione, respectively. All structures of the newly synthesized compounds were elucidated by elemental analysis, spectral data, and alternative synthetic methods whenever possible. Newly compounds are capable of high inhibiting the growth of bacteria (gram positive and gram negative).
引用
收藏
页码:1746 / 1754
页数:9
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