Plasma lipids oxidizeability in patients with occlusive atherosclerosis of lower extremities and ischemic heart disease

被引：0

作者：

Dadvani, IA

Syrkin, AL

Azizova, OA

Shcherbyuk, AN

Dumikyan, AS

Artyukhina, EG

Ulyanov, DA

Solovieva, NP

Dudnik, LB

机构：

[1] IM Sechenov Med Acad, Moscow 119881, Russia

[2] Res Inst Physiochem Med, Moscow 119828, Russia

来源：

KARDIOLOGIYA | 2005年 / 45卷 / 04期

关键词：

atherosclerosis; lower extremities; ischemic heart disease; lipoproteins; oxidation;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Dynamics of lipoprotein oxidation in blood plasma was studied by Cu-induced plasma oxidation in 114 patients with atherosclerosis of lower extremities of various severity with and without ischemic heart disease. Preparedness of plasma lipoproteins to oxidation in patients was higher than in healthy subjects. Degree of oxidizeability increased with increase of severity and extent of atherosclerosis and was highest in patients with atherosclerosis of lower extremities and ischemic heart disease. There were no significant differences between groups of patients with various severity and extent of atherosclerosis in levels of total cholesterol and triglycerides as well as in other parameters of lipid spectrum. Correlation analysis revealed no relationship between age of patients and degree of plasma oxidizeability.

引用

页码：55 / 60

页数：6

共 36 条

[21] Oxidative structural modifications of low density lipoprotein in homozygous familial hypercholesterolemia [J].