Methotrexate as a possible trigger of macrophage activation syndrome in systemic juvenile idiopathic arthritis

被引：0

作者：

Ravelli, A ^{[1
]}

Caria, MC ^{[1
]}

Buratti, S ^{[1
]}

Malattia, C ^{[1
]}

Temporini, F ^{[1
]}

Martini, A ^{[1
]}

机构：

[1] Univ Pavia, Ist Ricovero & Cura Carattere Sci S Matteo, Dipartimento Sci Peidat, I-27100 Pavia, Italy

来源：

JOURNAL OF RHEUMATOLOGY | 2001年 / 28卷 / 04期

关键词：

methotrexate; hemophagocytosis; macrophage activation syndrome; juvenile arthritis;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Macrophage activation syndrome (MAS) is a potentially life threatening complication of chronic: rheumatic diseases, particularly systemic juvenile idiopathic arthritis (JIA). A number of triggers have been related to the development of MAS, including viral infections, nonsteroidal antiinflammatory drug therapy, and gold salt injections. We describe a patient with systemic JIA who developed MAS shortly after receiving methotrexate. suggesting that this drug can be regarded as a potential trigger of MAS in children with JIA.

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页码：865 / 867

页数：3

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