In vitro investigation of bioactivities of solid-state fermented lupin, quinoa and wheat using Lactobacillus spp.

被引：81

作者：

Ayyash, Mutamed ^{[1
]}

Johnson, Stuart K. ^{[2
]}

Liu, Shao-Quan ^{[3
]}

Mesmari, Nouf ^{[1
]}

Dahmani, Shaikhah ^{[1
]}

Al Dhaheri, Ayesha S. ^{[4
]}

Kizhakkayil, Jaleel ^{[4
]}

机构：

[1] UAEU, Coll Food & Agr, Dept Food Sci, POB 1555, Al Ain, U Arab Emirates

[2] Curtin Univ, Curtin Hlth Innovat Res Inst, Sch Mol & Life Sci, Perth, WA 6845, Australia

[3] Natl Univ Singapore, Dept Chem, Food Sci & Technol Programme, S14 Level 5,Sci Dr 2, Singapore 117542, Singapore

[4] UAEU, Coll Food & Agr, Nutr & Hlth Sci, POB 1555, Al Ain, U Arab Emirates

来源：

FOOD CHEMISTRY | 2019年 / 275卷

关键词：

Cereal; Fermentation; Probiotic; Antihypertensive; Anticancer; ANTIOXIDANT PROPERTIES; ALPHA-GLUCOSIDASE; CAMEL MILK; CEREAL-GRAINS; BOVINE-MILK; PEPTIDES; HEALTH; ANTICANCER; AMYLASE; FOODS;

D O I：

10.1016/j.foodchem.2018.09.031

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

This study is an in-vitro investigation of the health-promoting properties of fermented whole-grain lupin, quinoa and wheat, using 72 h solid-state fermentation by Lactobacillus reuteri K777 and Lb. plantarum K779. Antiproliferative activity against Caco-2 and MCF-7 cancer cell lines (tumour cell lines of intestinal and mammary origin, respectively) was investigated, as well as alpha-amylase and alpha-glucosidase inhibition, antihypertensive, antioxidant and proteolytic activities. ABTS antioxidant activities of fermented lupin (FL, 55% w/v), quinoa (FQ, 55% w/v) and wheat (FW, 55% w/v) ranged from similar to 12.0% to 55.0%,similar to 17.6% to 73.0%, and similar to 29.0% to 26.0%, respectively. Lupin, quinoa and wheat fermented by L. plantarum had pronounced antihypertensive activities (similar to 85%). The alpha-glucosidase inhibition in FL was higher than that of FQ and FW. The magnitude of the antiproliferative activities of FL was markedly greater (p < 0.05) than of FQ and FW by approximately three-fold and two-folds against Caco-2 and MCF-7 cell lines, respectively.

引用

页码：50 / 58

页数：9

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