A selective Fluorescence Chemosensor: Pyrene motif Schiff base derivative for detection of Cu2+ ions in living cells

被引：31

作者：

Saravanan, Arjunan ^{[1
]}

Subashini, Gopalan ^{[2
]}

Shyamsivappan, Selvaraj ^{[2
]}

Suresh, Thangaraj ^{[2
]}

Kadirvelu, Krishna ^{[1
]}

Bhuvanesh, Nanjan ^{[3
]}

Nandhakumar, Raju ^{[3
]}

Mohan, Palathurai Subramaniam ^{[2
]}

机构：

[1] DRDO BU CLS, Bharathiar Univ Campus, Coimbatore 641046, Tamil Nadu, India

[2] Bharathiar Univ, Sch Chem Sci, Coimbatore 641046, Tamil Nadu, India

[3] Karunya Inst Technol & Sci, Dept Chem, Coimbatore 641114, Tamil Nadu, India

来源：

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY | 2018年 / 364卷

关键词：

Pyrene; Chemosensor; Copper ion; DFT calculation; Bioimaging; SENSITIVE DETECTION; COPPER; CU(II); PROBE; RECOGNITION; ALZHEIMERS; PLATFORM; SENSORS; BINDING; PRION;

D O I：

10.1016/j.jphotochem.2018.06.021

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A Schiff-base molecule, pyrene motif chemosensor 1 has been synthesized and performed for the fluorescent detection of Cu2+ ions via the inhibition of the photoinduced electron transfer (PET) process. Results were observed the exceptional selectivity towards Cu2+ in DMSO-H2O, (1:1 v/v, HEPES = 50 mM, pH = 7.4) and the association constant (K-a) for chemosensor 1 was binding to Cu2+ system have a value of 1.16 x 10(4) M-1. In addition, the chemosensor 1 has been used as a fluorescence probe for detecting Cu2+ ions in living cells and its binding phenomenon abilities were confirmed by bio-imaging and spectroscopic methods.

引用

页码：424 / 432

页数：9

共 53 条

[1] On-site fuel electroanalysis: Determination of lead, copper and mercury in fuel bioethanol by anodic stripping voltammetry using screen-printed gold electrodes [J].