SYNTHESIS AND ANTIMICROBIAL EVALUATION OF SOME NEW PYRIDINE BASED HETEROCYCLES

被引：20
作者：
Darwish, Elham S. [1 ]
Kheder, Nabila A. [1 ]
Farag, Ahmad M. [1 ]
机构：
[1] Cairo Univ, Fac Sci, Dept Chem, Giza 12613, Egypt
来源：
HETEROCYCLES | 2010年 / 81卷 / 10期
关键词：
3-Oxo-N-(pyridin-2-yl)butanamide; Hydrazonoyl Chloride; 1,3,4-Thiadiazole; Sulfonamide; Antimicrobial Evaluation; N-PHENYLPYRAZOLE DERIVATIVES; 1,3,4-THIADIAZOLE DERIVATIVES; THIOPHENE DERIVATIVES; PYRAZOLE; AGENTS; RING;
D O I：
10.3987/COM-10-11999
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A facile and convenient synthesis of pyridine, pyridazine, 2(3H)-1,3,4-thiadiazole and pyrazole derivatives incorporating a pyridine-2-ylcarboxamido moiety via the versatile, readily accessible 3-oxo-N-(pyridin-2-yl)butanamide is described. Antimicrobial evaluation of some selected examples from the synthesized products was carried out and showed moderate activity.
引用
收藏
页码：2247 / 2256
页数：10
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