Covalent modification of calcium hydroxyapatite surface by grafting phenyl phosphonate moieties

被引：32

作者：

Aissa, Abdallah

Debbabi, Mongi

Gruselle, Michel

Thouvenot, Rene

Gredin, Patrick

Traksmaa, Rainer

Tonsuaadu, Kaia

机构：

[1] Univ Paris 06, CNRS, UMR 7071,FR 2769, Lab Chim Inorgan & Mat Mol, F-75252 Paris 05, France

[2] Fac Sci Monastir, Lab Physico Chim Mat, Monastir 5019, Tunisia

[3] Univ Paris 06, CNRS, FR 2482,UMR 7574, Lab Chim Mat Condensee, F-75252 Paris, France

[4] Tallinn Univ Technol, Lab Inorgan Mat, EE-19086 Tallinn, Estonia

来源：

JOURNAL OF SOLID STATE CHEMISTRY | 2007年 / 180卷 / 08期

关键词：

hydroxyapatite; phosphonate; P-31; NMR; hybrid materials;

D O I：

10.1016/j.jssc.2007.05.016

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The reaction between phenyl phosphonic dichloride (C6H5P(O)Cl-2) and synthetic calcium hydroxy- and fluorapatite has been investigated. The presence of mono- or polymeric (C6H5PO) fragment bound to hydroxyapatite was evidenced by IR, and solid-state P-31 NMR spectroscopy. X-ray powder analysis has shown that the apatitic structure remains unchanged during the reaction. In contrast, no reaction was found using fluorapatite. According to the results found for these two different apatites a mechanism was proposed for the formation of covalent P-O-P bonds as the result of a reaction between the C6H5P(O)Cl-2 organic reagent and (HPO4)(-) and/or OH- ions of the hydroxyapatite. (C) 2007 Elsevier Inc. All rights reserved.

引用

页码：2273 / 2278

页数：6

共 25 条

[21] Modelling the interaction of several bisphosphonates with hydroxyapatite using the generalised AMBER force field [J].