Interference of homonuclear decoupling and exchange in the solid-state NMR of perfluorocyclohexane

We observe an interference between RF irradiation used for homonuclear decoupling of F-19 and conformational exchange in the C-13 spectrum of perfluorocyclohexane. We show that these effects can be readily reproduced in simulation, and characterise their dependence on the various NMR and experimental parameters. Their application to observing exchange rates on the kHz timescale is evaluated with respect to T-1p measurements and the connections between the two approaches established. The implications for experiments that use homonuclear decoupling of H-1 to resolve (1)J(CH) couplings in the solid-state are also evaluated in detail. (C) 2003 Elsevier Science (USA). All rights reserved.