D-Glucans from edible mushrooms: A review on the extraction, purification and chemical characterization approaches

被引：161
作者：
Ruthes, Andrea Caroline [1 ]
Smiderle, Fhernanda Ribeiro [1 ]
Iacomini, Marcello [1 ]
机构：
[1] Univ Fed Parana, Ctr Politecn, Dept Bioquim & Biol Mol, BR-81531980 Curitiba, Parana, Brazil
来源：
CARBOHYDRATE POLYMERS | 2015年 / 117卷
关键词：
D-Glucans; Edible mushrooms; Extraction; Purification; Chemical characterization; BETA-D-GLUCAN; WATER-SOLUBLE POLYSACCHARIDES; STRUCTURAL-CHARACTERIZATION; FRUIT BODIES; ANTITUMOR-ACTIVITY; AGARICUS-BISPORUS; MOLECULAR-WEIGHT; PLEUROTUS-OSTREATUS; ANTIOXIDANT; HETEROGALACTAN;
D O I：
10.1016/j.carbpol.2014.10.051
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
D-Glucans from edible mushrooms present diversified chemical structures. The most common type consists of a backbone of beta-D-glucose (1 -> 3)-linked frequently branched at 0-6 by beta-D-glucose residues as side chains. However it is possible to distinguish alpha-, beta- and mixed D-glucans. Further discrimination could be made on the basis of glycosidic bond position in a pyranoid ring, distribution of specific glycosidic bonds along the chain, branching and molecular weight. The present manuscript reviews the processes of extraction, purification and chemical characterization of D-glucans, such as NMR studies, methylation analysis, Smith degradation, and some other methodologies employed in carbohydrate chemistry characterization. In addition, these polysaccharides are important because they can provide many therapeutic benefits related to their biological activity in animals and humans, either immunostimulatory activity, inhibiting tumor growth, as well as exerting antinociceptive and anti-inflammatory action, among others, which are usually attached to their structure, molecular weight and degree of branching. (C) 2014 Published by Elsevier Ltd.
引用
收藏
页码：753 / 761
页数：9
相关论文
共 80 条
[1]   A NEW PROCEDURE FOR THE DETERMINATION OF THE FINE STRUCTURE OF POLYSACCHARIDES [J].
ABDELAKHER, M ;
HAMILTON, JK ;
MONTGOMERY, R ;
SMITH, F .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1952, 74 (19) :4970-4971
[2]   Polysaccharides from the fruit bodies of the basidiomycete Laetiporus sulphureus (Bull.: Fr.) Murr [J].
Alquini, G ;
Carbonero, ER ;
Rosado, FR ;
Cosentino, C ;
Iacomini, M .
FEMS MICROBIOLOGY LETTERS, 2004, 230 (01) :47-52
[3]   An unusual water-soluble β-glucan from the basidiocarp of the fungus Ganoderma resinaceum [J].
Amaral, Alex E. ;
Carbonero, Elaine R. ;
Simao, Rita de Cassia G. ;
Kadowaki, Marina K. ;
Sassaki, Guilherme L. ;
Osaku, Clarice A. ;
Gorin, Philip A. J. ;
Iacomini, Marcello .
CARBOHYDRATE POLYMERS, 2008, 72 (03) :473-478
[4]   Correlation of branching structure of mushroom β-glucan with its physiological activities [J].
Bae, In Young ;
Kim, Hye Won ;
Yoo, Hyun Jae ;
Kim, Eun Suh ;
Lee, Suyong ;
Park, Dong Yun ;
Lee, Hyeon Gyu .
FOOD RESEARCH INTERNATIONAL, 2013, 51 (01) :195-200
[5]  
Bhanja SK., 2014, Bioactive Carbohydrates and Dietary Fibre, V3, P52, DOI [DOI 10.1016/J.BCDF.2014.01.004, 10.1016/j.bcdf.2014.01.004]
[6]   A novel water-soluble β-(1→6)-D-glucan isolated from the fruit bodies of Bulgaria inquinans (Fries) [J].
Bi, Hongtao ;
Ni, Xiuzhen ;
Liu, Xiaoyu ;
Iteku, Jeff ;
Tai, Guihua ;
Zhou, Yifa ;
Zhao, Jimin .
CARBOHYDRATE RESEARCH, 2009, 344 (10) :1254-1258
[7]   NMR spectroscopy in the study of carbohydrates: Characterizing the structural complexity [J].
Bubb, WA .
CONCEPTS IN MAGNETIC RESONANCE PART A, 2003, 19A (01) :1-19
[8]   Lentinus edodes heterogalactan: Antinociceptive and anti-inflammatory effects [J].
Carbonero, E. R. ;
Gracher, A. H. P. ;
Komura, D. L. ;
Marcon, R. ;
Freitas, C. S. ;
Baggio, C. H. ;
Santos, A. R. S. ;
Torri, G. ;
Gorin, P. A. J. ;
Iacomini, M. .
FOOD CHEMISTRY, 2008, 111 (03) :531-537
[9]   Chemical and biological properties of a highly branched β-glucan from edible mushroom Pleurotus sajor-caju [J].
Carbonero, Elaine R. ;
Ruthes, Andrea Caroline ;
Freitas, Cristina Setim ;
Utrilla, Pillar ;
Galvez, Julio ;
da Silva, Estefania Viano ;
Sassaki, Guilherme Lanzi ;
James Gorin, Philip Albert ;
Iacomini, Marcello .
CARBOHYDRATE POLYMERS, 2012, 90 (02) :814-819
[10]   A β-glucan from the fruit bodies of edible mushrooms Pleurotus eryngii and Pleurotus ostreatoroseus [J].
Carbonero, Elaine R. ;
Gracher, Ana Helena P. ;
Smiderle, Fhernanda R. ;
Rosado, Fabio R. ;
Sassaki, Guilherme L. ;
Gorin, Philip A. J. ;
Iacomini, Marcello .
CARBOHYDRATE POLYMERS, 2006, 66 (02) :252-257
12345678