Aluminium Oxide Thin-Film Based In Vitro Cell-Substrate Sensing Device for Monitoring Proliferation of Myoblast Cells

被引：4

作者：

Kasiviswanathan, Uvanesh ^{[1
]}

Balavigneswaran, Chelladurai Karthikeyan ^{[1
]}

Kumar, Chandan ^{[2
]}

Poddar, Suruchi ^{[1
]}

Jit, Satyabrata ^{[2
]}

Sharma, Neeraj ^{[1
]}

Mahto, Sanjeev Kumar ^{[1
]}

机构：

[1] Banaras Hindu Univ, Sch Biomed Engn, Indian Inst Technol, Varanasi 221005, Uttar Pradesh, India

[2] Banaras Hindu Univ, Dept Elect Engn, Indian Inst Technol, Varanasi 221005, Uttar Pradesh, India

来源：

IEEE TRANSACTIONS ON NANOBIOSCIENCE | 2021年 / 20卷 / 03期

关键词：

Cells (biology); Monitoring; Substrates; Sensors; In vitro; Indium tin oxide; Aluminum oxide; Aluminium oxide; cell interaction; MIM structure; myoblast cells; mathematical modelling; DIELECTRIC-PROPERTIES; BIOSENSORS; MICRO; TIO2; BIOCOMPATIBILITY; NANOPARTICLES; FABRICATION; ADHESION; BEHAVIOR; DIOXIDE;

D O I：

10.1109/TNB.2021.3068318

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We demonstrate cell-substrate interaction on aluminium oxide thin-film in metal-insulator-metal structure followed by the change in dielectric characteristics of Al2O3 as a function of progression of cellular growth. The theoretical calculation of the fabricated biosensor reveals that the changes in the intrinsic elemental parameters are mainly attributed to the cell-induced behavioural changes.

引用

页码：331 / 337

页数：7

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