Aluminium Oxide Thin-Film Based In Vitro Cell-Substrate Sensing Device for Monitoring Proliferation of Myoblast Cells

被引:4
作者
Kasiviswanathan, Uvanesh [1 ]
Balavigneswaran, Chelladurai Karthikeyan [1 ]
Kumar, Chandan [2 ]
Poddar, Suruchi [1 ]
Jit, Satyabrata [2 ]
Sharma, Neeraj [1 ]
Mahto, Sanjeev Kumar [1 ]
机构
[1] Banaras Hindu Univ, Sch Biomed Engn, Indian Inst Technol, Varanasi 221005, Uttar Pradesh, India
[2] Banaras Hindu Univ, Dept Elect Engn, Indian Inst Technol, Varanasi 221005, Uttar Pradesh, India
关键词
Cells (biology); Monitoring; Substrates; Sensors; In vitro; Indium tin oxide; Aluminum oxide; Aluminium oxide; cell interaction; MIM structure; myoblast cells; mathematical modelling; DIELECTRIC-PROPERTIES; BIOSENSORS; MICRO; TIO2; BIOCOMPATIBILITY; NANOPARTICLES; FABRICATION; ADHESION; BEHAVIOR; DIOXIDE;
D O I
10.1109/TNB.2021.3068318
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
We demonstrate cell-substrate interaction on aluminium oxide thin-film in metal-insulator-metal structure followed by the change in dielectric characteristics of Al2O3 as a function of progression of cellular growth. The theoretical calculation of the fabricated biosensor reveals that the changes in the intrinsic elemental parameters are mainly attributed to the cell-induced behavioural changes.
引用
收藏
页码:331 / 337
页数:7
相关论文
共 54 条
  • [1] AlFadhli S, 2012, MUTATIONS HUMAN GENE
  • [2] Amini M, 2018, J Electr Bioimpedance, V9, P142, DOI 10.2478/joeb-2018-0019
  • [3] Labeling of human mesenchymal stem cells with different classes of vital stains: robustness and toxicity
    Andrzejewska, Anna
    Jablonska, Anna
    Seta, Martyna
    Dabrowska, Sylwia
    Walczak, Piotr
    Janowski, Miroslaw
    Lukomska, Barbara
    [J]. STEM CELL RESEARCH & THERAPY, 2019, 10 (1)
  • [4] Cellular impedance biosensors for drug screening and toxin detection
    Asphahani, Fareid
    Zhang, Miqin
    [J]. ANALYST, 2007, 132 (09) : 835 - 841
  • [5] Tailored Chemical Properties of 4-Arm Star Shaped Poly(D,L-lactide) as Cell Adhesive Three-Dimensional Scaffolds
    Balavigneswaran, Chelladurai Karthikeyan
    Mahto, Sanjeev Kumar
    Subia, Bano
    Prabhakar, Arumugam
    Mitra, Kheyanath
    Rao, Vivek
    Ganguli, Munia
    Ray, Biswajit
    Maiti, Pralay
    Misra, Nira
    [J]. BIOCONJUGATE CHEMISTRY, 2017, 28 (04) : 1236 - 1250
  • [6] Nanoplasmonics-enhanced label-free imaging of endothelial cell monolayer integrity
    Banville, Frederic A.
    Moreau, Julien
    Chabot, Kevin
    Cattoni, Andrea
    Frohlich, Ulrike
    Bryche, Jean-Francois
    Collin, Stephane
    Charette, Paul G.
    Grandbois, Michel
    Canva, Michael
    [J]. BIOSENSORS & BIOELECTRONICS, 2019, 141
  • [7] Review paper: Progress in the Field of Conducting Polymers for Tissue Engineering Applications
    Bendrea, Anca-Dana
    Cianga, Luminita
    Cianga, Ioan
    [J]. JOURNAL OF BIOMATERIALS APPLICATIONS, 2011, 26 (01) : 3 - 84
  • [8] Engineering Substrate Topography at the Micro- and Nanoscale to Control Cell Function
    Bettinger, Christopher J.
    Langer, Robert
    Borenstein, Jeffrey T.
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (30) : 5406 - 5415
  • [9] Biocompatibility of cluster-assembled nanostructured TiO2 with primary and cancer cells
    Carbone, R
    Marangi, I
    Zanardi, A
    Giorgetti, L
    Chierici, E
    Berlanda, G
    Podestà, A
    Fiorentini, F
    Bongiorno, G
    Piseri, P
    Pelicci, PG
    Milani, P
    [J]. BIOMATERIALS, 2006, 27 (17) : 3221 - 3229
  • [10] Fragmental Frequency Analysis Method to Estimate Electrical Cell Parameters from Bioimpedance Study
    Das, Debanjan
    Kamil, Farhan Ahmad
    Agrawal, Snehil
    Biswas, Karabi
    Das, Soumen
    [J]. IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT, 2014, 63 (08) : 1991 - 2000