Biomimicking Nano-Micro Binary Polymer Brushes for Smart Cell Orientation and Adhesion Control

被引：42

作者：

Chen, Lina ^{[1
]}

Xie, Zhuang ^{[1
,2
,3
]}

Gan, Tiansheng ^{[4
]}

Wang, Yi ^{[5
]}

Zhang, Guangzhao ^{[4
]}

Mirkin, Chad A. ^{[2
,3
]}

Zheng, Zijian ^{[1
]}

机构：

[1] Hong Kong Polytech Univ, Nanotechnol Ctr, Inst Text & Clothing, Kowloon, Hong Kong, Peoples R China

[2] Northwestern Univ, Dept Chem, 2145 Sheridan Rd, Evanston, IL 60208 USA

[3] Northwestern Univ, Int Inst Nanotechnol, 2145 Sheridan Rd, Evanston, IL 60208 USA

[4] South China Univ Technol, Fac Mat Sci & Engn, Guangzhou 510640, Guangdong, Peoples R China

[5] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Kowloon, Hong Kong, Peoples R China

来源：

SMALL | 2016年 / 12卷 / 25期

基金：

美国国家科学基金会;

关键词：

PEN NANODISPLACEMENT LITHOGRAPHY; ALIGNMENT; MATRIX; PROLIFERATION; FABRICATION; NANOGROOVE; SURFACES;

D O I：

10.1002/smll.201600634

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new biomimetic surface named nano-micro binary polymer brushes is fabricated by large-area bench-top dip-pen nanodisplacement lithography technique. It is composed of gelatin-modified poly( glycidyl methacrylate) nanolines which are spaced by microstripes of poly(N-isopropylacrylamide). Cells are not only adhered and oriented well on the re-used surface, but also detachable from the surface with well-preserved extracellular matrix and aligned morphology.

引用

页码：3400 / +

页数：8

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