Chronic osteomyelitis caused by Achromobacter xylosoxidans following orthopaedic trauma: A case report and review of the literature

被引：6

作者：

Imani, Sahand ^{[1
]}

Wijetunga, Asanka ^{[2
]}

Shumborski, Sarah ^{[1
]}

O'Leary, Edmund ^{[1
]}

机构：

[1] Hornsby Ku Ring Gai Hosp, Dept Orthopaed Surg, Sydney, NSW, Australia

[2] Univ Sydney, Sch Med, Sydney, NSW, Australia

来源：

IDCASES | 2021年 / 25卷

关键词：

Achromobacter xylosoxidans; Chronic; Osteomyelitis; Femur; Trauma; Management; MANAGEMENT; BACTEREMIA; RESISTANCE; OUTCOMES; RISK;

D O I：

10.1016/j.idcr.2021.e01211

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Background: Achromobacter xylosoxidans is an opportunistic environmental aerobe. In cases where A. xylosoxidans infects humans, it most commonly manifests as bacteraemia in the immunosuppressed. A. xylosoxidans causing chronic osteomyelitis is rare, particularly in the immunocompetent and young. Case: We present the case of a 23-year-old man with chronic osteomyelitis of the right femur caused by co-infection of A. xylosoxidans and Staphylococcus aureus. Five years earlier, he had sustained a right femur fracture and was treated with intramedullary fixation at a peripheral hospital in a developing nation. Past medical history was otherwise unremarkable. Management comprised of surgical debridement and culture-directed antibiotic therapy, resulting in clinical cure. Conclusion: In the context of local trauma and previous surgery, osteomyelitis caused by atypical pathogens must be considered. A multidisciplinary approach commensurate with duration and severity of infection and tailored to the causative organism is paramount. (C) 2021 The Author(s). Published by Elsevier Ltd.

引用

页数：5

共 29 条

[1] Bacteremia caused by Achromobacter and Alcaligenes species in 46 patients with cancer (1989-2003) [J].

Aisenberg, G ;

Rolston, KV ;

Safdar, A .

CANCER, 2004, 101 (09) :2134-2140

[2] Achromobacter xylosoxidans is the predominant Achromobacter species isolated from diverse non- respiratory samples [J].

Amoureux, L. ;

Bador, J. ;

Verrier, T. ;

Mjahed, H. ;

De Curraize, C. ;

Neuwirth, C. .

EPIDEMIOLOGY AND INFECTION, 2016, 144 (16) :3527-3530

[3] Characterization of a naturally occurring class D β-lactamase from Achromobacter xylosoxidans [J].

Doi, Yohei ;

Poirel, Laurent ;

Paterson, David L. ;

Nordmann, Patrice .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2008, 52 (06) :1952-1956

[4] OSTEOMYELITIS SECONDARY TO TRAUMA OR INFECTED CONTIGUOUS SOFT-TISSUE [J].

DUBEY, L ;

KRASINSKI, K ;

HERNANZSCHULMAN, M .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 1988, 7 (01) :26-34

[5] Achromobacter xylosoxidans bacteremia:: A 10-year analysis of 54 cases [J].

Gómez-Cerezo, J ;

Suárez, I ;

Ríos, JJ ;

Peña, P ;

de Miguel, MJG ;

de José, M ;

Monteagudo, O ;

Linares, P ;

Barbado-Cano, A ;

Vázquez, JJ .

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2003, 22 (06) :360-363

[6]

Hatzenbuehler J, 2011, AM FAM PHYSICIAN, V84, P1027

[7]

HODDY DM, 1991, AM J DIS CHILD, V145, P599

[8] Genomic Insights into Intrinsic and Acquired Drug Resistance Mechanisms in Achromobacter xylosoxidans [J].

Hu, Yongfei ;

Zhu, Yuying ;

Ma, Yanan ;

Liu, Fei ;

Lu, Na ;

Yang, Xi ;

Luan, Chunguang ;

Yi, Yong ;

Zhu, Baoli .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2015, 59 (02) :1152-1161

[9] Chronic osteomyelitis increases long-term mortality risk in the elderly: a nationwide population-based cohort study [J].

Huang, Chien-Cheng ;

Tsai, Kang-Ting ;

Weng, Shih-Feng ;

Lin, Hung-Jung ;

Huang, Hung-Sheng ;

Wang, Jhi-Joung ;

Guo, How-Ran ;

Hsu, Chien-Chin .

BMC GERIATRICS, 2016, 16

[10] CLINICAL AND LABORATORY CHARACTERISTICS OF ACHROMOBACTER-XYLOSOXIDANS INFECTION [J].

IGRASIEGMAN, Y ;

CHMEL, H ;

COBBS, C .

JOURNAL OF CLINICAL MICROBIOLOGY, 1980, 11 (02) :141-145

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