A tandem carbanion addition/carbon-carbon bond cleavage yields alkynyl ketones

被引：57

作者：

Kamijo, S ^{[1
]}

Dudley, GB ^{[1
]}

机构：

[1] Florida State Univ, Dept Chem & Biochem, Tallahassee, FL 32306 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2005年 / 127卷 / 14期

关键词：

D O I：

10.1021/ja050663m

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Carbanion addition to vinylogous acid triflates triggers carbon-carbon bond cleavage to form alkynyl ketones under mild conditions. Mechanistic factors affecting the cleavage event and its relationship to complementary fragmentations are discussed. A range of tethered keto-alkynes are obtained by a unified approach. Copyright © 2005 American Chemical Society.

引用

页码：5028 / 5029

页数：2

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