Isolation of a Candida glabrata homologue of RAP1, a regulator of transcription and telomere function in Saccharomyces cereviciae

被引：16

作者：

Haw, R ^{[1
]}

Yarragudi, AD ^{[1
]}

Uemura, H ^{[1
]}

机构：

[1] AIST Tsukuba Cent 6, Natl Inst Adv Ind Sci & Technol, Tsukuba, Ibaraki 3058566, Japan

来源：

YEAST | 2001年 / 18卷 / 14期

关键词：

transcription; silencing; telomere; RAP1; Candida glabrata; Saccharomyces cerevisiae;

D O I：

10.1002/yea.775

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

To study the function of RAP1, an essential gene involved in the regulation of transcriptional activation, silencing and the telomere function in Saccharomyces ceresvisiae, we isolated a Candida glabrata gene that complements the growth defect of a S. cerevisiae rap1 conditional mutant. The DNA sequence of the cloned gene, which we designated CgRAP1, predicted a 2064 bp open reading frame encoding a 687 amino acid protein with an overall identity of 65% and a similarity of 78% to Rap1p from S. cerevisiae. Its DDBJ/EMBL/GenBank Accession No. is AB055655. Copyright (C) 2001 John Wiley & Sons, Ltd.

引用

页码：1277 / 1284

页数：8

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