Synthesis of the C7-C15 trans decalin portion of the natural antibiotic tetrodecamycin

被引：22

作者：

Warrington, JM ^{[1
]}

Barriault, L ^{[1
]}

机构：

[1] Univ Ottawa, Dept Chem, Ottawa, ON K1N 6N5, Canada

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 21期

关键词：

D O I：

10.1021/ol051715f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The tandem oxy-Cope/ene/Claisen rearrangement has been developed in our laboratory as a powerful method for rapid construction of complex Decalin cores. Herein, we describe the use of this method to generate the Decalin core of the natural antibiotic tetrodecamycin (1) bearing six contiguous stereocenters.

引用

页码：4589 / 4592

页数：4

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