Characterisation of a mobilisable plasmid conferring florfenicol and chloramphenicol resistance in Actinobacillus pleuropneumoniae

被引:34
作者
Bosse, Janine T. [1 ]
Li, Yanwen [1 ]
Atherton, Tom G. [1 ]
Walker, Stephanie [1 ]
Williamson, Susanna M. [2 ]
Rogers, Jon [2 ]
Chaudhuri, Roy R. [3 ]
Weinert, Lucy A. [3 ]
Holden, Matthew T. G. [4 ]
Maskell, Duncan J. [3 ]
Tucker, Alexander W. [3 ]
Wren, Brendan W. [5 ]
Rycroft, Andrew N. [6 ]
Langford, Paul R. [1 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, Dept Med, Paediat Sect, London W2 1PG, England
[2] Anim & Plant Hlth Agcy APHA Bury St Edmunds, Bury St Edmunds IP33 2RX, Suffolk, England
[3] Univ Cambridge, Dept Vet Med, Cambridge CB3 0ES, England
[4] Wellcome Trust Sanger Inst, Cambridge CB10 1SA, England
[5] Univ London London Sch Hyg & Trop Med, Fac Infect & Trop Dis, London WC1E 7HT, England
[6] Univ London Royal Vet Coll, Dept Pathol & Pathogen Biol, Hatfield AL9 7TA, Herts, England
基金
英国生物技术与生命科学研究理事会; 英国惠康基金;
关键词
RESPIRATORY-TRACT PATHOGENS; ANTIMICROBIAL RESISTANCE; PASTEURELLA-MULTOCIDA; SUSCEPTIBILITY; BOVINE; PIGS; IDENTIFICATION; BACTERIA; GERMANY; CATTLE;
D O I
10.1016/j.vetmic.2015.05.020
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The complete nucleotide sequence of a 7.7 kb mobilisable plasmid (pM3446F), isolated from a florfenicol resistant isolate of Actinobacillus pleuropneumoniae, showed extended similarity to plasmids found in other members of the Pasteurellaceae containing the floR gene as well as replication and mobilisation genes. Mobilisation into other Pasteurellaceae species confirmed that this plasmid can be transferred horizontally. (C) 2015 The Authors. Published by Elsevier B.V.
引用
收藏
页码:279 / 282
页数:4
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