Effects of different intensities of acute exercise on flow-mediated dilatation in patients with coronary heart disease

被引：20
作者：
Farsidfar, Farsid [1 ]
Kasikcioglu, Erdem [2 ]
Oflaz, Huseyin [1 ]
Kasikcioglu, Derya [3 ]
Meric, Mehmet [1 ]
Umman, Sabahattin [1 ]
机构：
[1] Istanbul Univ, Istanbul Fac Med, Dept Cardiol, Istanbul, Turkey
[2] Dept Sports Med, Istanbul, Turkey
[3] Cerrahpasa Fac Med, Dept Nucl Med, Istanbul, Turkey
来源：
INTERNATIONAL JOURNAL OF CARDIOLOGY | 2008年 / 124卷 / 03期
关键词：
exercise; endothelial function; flow-mediated dilatation; coronary artery disease; cardiac rehabilitation;
D O I：
10.1016/j.ijcard.2006.11.243
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
It is known that regular exercise training improves endothelial dysfunction in coronary artery disease, but, little is known concerning different intensities of acute exercise on endothelial function. We evaluated anaerobic threshold and peak oxygen uptake level of acute exercise on flow-mediated dilatation in patients with stable coronary artery disease. Endothelium-independent vasoreactivity in patients showed a trend with increase at threshold level exercise; however, it was significantly decreased at peak level exercise. Moderate intensity exercise (nearly anaerobic threshold level) should be recommended a therapeutic and preventative strategy for starting of cardiac rehabilitation program in patients with coronary artery disease. (c) 2007 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：372 / 374
页数：3
相关论文
共 10 条
[1]   Exercise training enhances endothelial function in young men [J].
Clarkson, P ;
Montgomery, HE ;
Mullen, MJ ;
Donald, AE ;
Powe, AJ ;
Bull, T ;
Jubb, M ;
World, M ;
Deanfield, JE .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1999, 33 (05) :1379-1385
[2]   Regular physical exercise corrects endothelial dysfunction and improves exercise capacity in patients with chronic heart failure [J].
Hambrecht, R ;
Fiehn, E ;
Weigl, C ;
Gielen, S ;
Hamann, C ;
Kaiser, R ;
Yu, JT ;
Adams, V ;
Niebauer, J ;
Schuler, G .
CIRCULATION, 1998, 98 (24) :2709-2715
[3]   Endothelial flow-mediated dilatation and exercise capacity in highly trained endurance athletes [J].
Kasikcioglu, E ;
Oflaz, H ;
Kaskcioglu, HA ;
Kayserilioglu, A ;
Umman, S ;
Meric, M .
TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, 2005, 205 (01) :45-51
[4]   Moderate vs. high exercise intensity: Differential effects on aerobic fitness, cardiomyocyte contractility, and endothelial function [J].
Kemi, OJ ;
Haram, PM ;
Loennechen, JP ;
Osnes, JB ;
Skomedal, T ;
Wisloff, U ;
Ellingsen, O .
CARDIOVASCULAR RESEARCH, 2005, 67 (01) :161-172
[5]   Exercise and the endothelial cell [J].
Marsh, SA ;
Coombes, JS .
INTERNATIONAL JOURNAL OF CARDIOLOGY, 2005, 99 (02) :165-169
[6]   Exercise capacity and mortality among men referred for exercise testing [J].
Myers, J ;
Prakash, M ;
Froelicher, V ;
Do, D ;
Partington, S ;
Atwood, JE .
NEW ENGLAND JOURNAL OF MEDICINE, 2002, 346 (11) :793-801
[7]   Individual assessment of intensity-level for exercise training in patients with coronary artery disease is necessary [J].
Nieuwland, W ;
Berkhuysen, MA ;
Van Veldhuisen, DJ ;
Rispens, P .
INTERNATIONAL JOURNAL OF CARDIOLOGY, 2002, 84 (01) :15-20
[8]   Relation between conduit vessel stiffness (Assessed by tonometry) and endothelial function (Assessed by flow-mediated dilatation) in patients with and without coronary heart disease [J].
Nigam, A ;
Mitchell, GF ;
Lambert, J ;
Tardif, JC .
AMERICAN JOURNAL OF CARDIOLOGY, 2003, 92 (04) :395-399
[9]   Physical activity and coronary heart disease in men - The Harvard Alumni Health Study [J].
Sesso, HD ;
Paffenbarger, RS ;
Lee, IM .
CIRCULATION, 2000, 102 (09) :975-980
[10]   Exercise type and intensity in relation to coronary heart disease in men [J].
Tanasescu, N ;
Leitzmann, MF ;
Rimm, EB ;
Willett, WC ;
Stampfer, MJ ;
Hu, FB .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2002, 288 (16) :1994-2000
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