Transient Changes in Preexposure Prophylaxis Use and Daily Sexual Behavior After the Implementation of COVID-19 Restrictions Among Men Who Have Sex With Men

被引：24
作者：
Jongen, Vita W. [1 ]
Zimmermann, Hanne M. L. [1 ]
Boyd, Anders [1 ,2 ]
Hoornenborg, Elske [1 ]
van den Elshout, Mark A. M. [1 ]
Davidovich, Udi [1 ,3 ]
van Duijnhoven, Yvonne T. H. P. [1 ]
de Vries, Henry J. C. [1 ,4 ]
Prins, Maria [1 ,5 ]
Schim van der Loeff, Maarten F. [1 ,5 ]
Coyer, Liza [1 ]
机构：
[1] Publ Hlth Serv Amsterdam, Dept Infect Dis, Nieuwe Achtergracht 100, NL-1018 WT Amsterdam, Netherlands
[2] HIV Monitoring Fdn, Amsterdam, Netherlands
[3] Univ Amsterdam, Dept Social Psychol, Amsterdam, Netherlands
[4] Univ Amsterdam, Amsterdam UMC, Amsterdam Infect & Immun AII, Dept Dermatol, Amsterdam, Netherlands
[5] Univ Amsterdam, Amsterdam UMC, Amsterdam Infect & Immun AII, Dept Infect Dis, Amsterdam, Netherlands
来源：
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES | 2021年 / 87卷 / 05期
关键词：
COVID-19; preexposure prophylaxis; HIV; prevention and control; sexual behavior; men who have sex with men; PREP; RISK; HIV;
D O I：
10.1097/QAI.0000000000002697
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Background: We assessed how the Dutch restrictions imposed on March 15, 2020, affected sexual behavior, preexposure prophylaxis (PrEP), and condom use among PrEP users in Amsterdam. Methods: We used data on (1) PrEP use, (2) anal sex acts, and (3) condom use, per partner type [steady partners (SPs), known casual partners (KCPs), and unknown casual partners (UCPs)], collected daily through a mobile application used between December 1, 2019, and June 30, 2020. We compared the period before versus after March 15, 2020, regarding average proportion of days per week at which each end point was reported and average proportion of anal sex acts covered by PrEP and/or condoms. Results: We included data from 136 men who have sex with men. After March 15, 2020, the proportion of days with anal sex increased with SPs [odds ratio (OR) = 1.26; 95% confidence interval (CI) = 1.10 to 1.44) and decreased with KCPs (OR = 0.73; 95% CI = 0.64 to 0.82) and UCPs (OR = 0.54; 95% CI = 0.48 to 0.61). Shifts in partner types were most profound immediately after March 15, 2020, whereas returning to prerestriction levels mid-May 2020. The proportion of days with PrEP use decreased from 74% before to 58% after March 15, 2020 (P < 0.001). After March 15, 2020, PrEP use during sex decreased with UCPs (beta = -0.36; 95% CI = -0.72 to 0.00) but not with SPs and KCPs. Condom use during sex decreased with KCPs (beta = -0.36; 95% CI = -0.67 to 0.04) and UCPs (beta = -0.24; 95% CI = -0.46 to 0.03) but not with SPs. Conclusions: MSM decreased sex with casual partners and increased sex with SP, but changes were transient. Decreases in sex acts with casual partners paralleled decreases in PrEP use. However, condom use during sex with casual partners decreased, indicating the importance of continued sexual health services, including sexually transmitted infections screening and PrEP care, during COVID-19 restrictions.
引用
收藏
页码：1111 / 1118
页数：8
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