High-maintenance proteins and hypertriglyceridemia

被引：4

作者：

Attie, Alan D. ^{[1
]}

机构：

[1] Univ Wisconsin, Dept Biochem, Madison, WI 53706 USA

来源：

NATURE GENETICS | 2007年 / 39卷 / 12期

关键词：

D O I：

10.1038/ng1207-1424

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Lipoprotein lipase, the enzyme that hydrolyzes fatty acids from triglycerides carried by circulating lipoproteins, resides on the surface of the capillary endothelium. Analysis of a hypertriglyceridemic mutant mouse has now identified a protein, LMF1, that is critical for the transport of active lipoprotein lipase through the secretory pathway.

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页码：1424 / 1425

页数：2

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