Total Synthesis of Cercidinin A via a Sequential Site-selective Acylation Strategy

被引：12

作者：

Shibayama, Hiromitsu ^{[1
]}

Ueda, Yoshihiro ^{[1
]}

Kawabata, Takeo ^{[1
]}

机构：

[1] Kyoto Univ, Inst Chem Res, Uji, Kyoto 6110011, Japan

来源：

CHEMISTRY LETTERS | 2020年 / 49卷 / 02期

关键词：

Site selectivity; Acylation; Ellagitannin; GALLIC ACID; (S)-HEXAHYDROXYDIPHENIC ACID; HEXAHYDROXYDIPHENIC ACID; GLUCOSE DERIVATIVES; ACYL; ELLAGITANNINS; CLEAVAGE; ESTERS; FUNCTIONALIZATION; CARBOHYDRATE;

D O I：

10.1246/cl.190872

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Total synthesis of cercidinin A (1) was achieved in 7 overall steps from D-glucose (9 steps from gallic acid) via sequential site-selective introduction of requisite galloyl groups into hydroxy groups of unprotected glucose. No protective groups were used for hydroxy groups of D-glucose throughout the total synthesis.

引用

页码：182 / 185

页数：4

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