Depression

被引：2953

作者：

Malhi, Gin S. ^{[1
,2
]}

Mann, J. John ^{[3
]}

机构：

[1] Univ Sydney, Sydney Med Sch Northern, Dept Acad Psychiat, Sydney, NSW, Australia

[2] Royal North Shore Hosp, CADE Clin, Sydney, NSW, Australia

[3] Columbia Univ, Dept Psychiat, Mol Imaging & Neuropathol Div, New York, NY USA

来源：

LANCET | 2018年 / 392卷 / 10161期

基金：

英国医学研究理事会;

关键词：

SEROTONIN REUPTAKE INHIBITORS; CLINICAL-PRACTICE GUIDELINES; STRESSFUL LIFE EVENTS; NEW-ZEALAND COLLEGE; TREATMENT-RESISTANT DEPRESSION; MAJOR DEPRESSION; ANTIDEPRESSANT MEDICATION; PSYCHOLOGICAL TREATMENTS; ANXIETY DISORDERS; ADULT DEPRESSION;

D O I：

10.1016/S0140-6736(18)31948-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Major depression is a common illness that severely limits psychosocial functioning and diminishes quality of life. In 2008, WHO ranked major depression as the third cause of burden of disease worldwide and projected that the disease will rank first by 2030.1 In practice, its detection, diagnosis, and management often pose challenges for clinicians because of its various presentations, unpredictable course and prognosis, and variable response to treatment.

引用

页码：2299 / 2312

页数：14

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