Dependence of broadband ultrasound attenuation on the elastic anisotropy of trabecular bone

The effect of trabecular elastic anisotropy on broadband ultrasound attenuation (BUA) and bone mineral density (BMD) was investigated with human and bovine cubic cancellous bones. Ultrasonic parameters describing trabecular anisotropy were found from the three orthogonal ultrasound velocities. BMD was measured using quantitative computed tomography. Three elastic anisotropy ratios were compared to BUA in all three directions and to BMD. The combined effect of anisotropic characteristics and BMD was also correlated with BUA. The results showed that the anisotropy ratios were significantly related to BUA (p < 0.05). There was, however, no correlation between BMD and the elastic anisotropy ratios. The combination of BMD and the anisotropy produced a significantly enhanced relationship with BUA.