2019 ESC/EAS Guidelines for management of dyslipidaemia: strengths and limitations

被引：34

作者：

Zeitouni, Michel ^{[1
]}

Sabouret, Pierre ^{[1
]}

Kerneis, Mathieu ^{[1
]}

Silvain, Johanne ^{[1
]}

Collet, Jean-Philippe ^{[1
]}

Bruckert, Eric ^{[2
,3
]}

Montalescot, Gilles ^{[1
]}

机构：

[1] Sorbonne Univ, Inst Cardiol, APHP, Dept Cardiol,ACTION Study Grp,INSERM,UMRS_1166, 47-83 Bld Hop, F-75013 Paris, France

[2] Sorbonne Univ, Cardio Metab Inst, 83 Bld Hop, F-75013 Paris, France

[3] Sorbonne Univ, Pitie Salpetriere Hosp, Dept Endocrinol, 83 Bld Hop, F-75013 Paris, France

来源：

EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY | 2021年 / 7卷 / 04期

关键词：

Dyslipidaemia; Guidelines; Statins; PCSSK9; inhibitors; CORONARY-HEART-DISEASE; CHOLESTEROL EFFLUX CAPACITY; JOINT TASK-FORCE; CARDIOVASCULAR-DISEASE; LDL CHOLESTEROL; STATIN THERAPY; HIGH-RISK; MYOCARDIAL-INFARCTION; EUROPEAN GUIDELINES; METABOLIC SYNDROME;

D O I：

10.1093/ehjcvp/pvaa077

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In 2019, the European Society of Cardiology and European Atherosclerosis Society released a new guideline document with substantial changes regarding the assessment of cardiovascular risk and treatments. The update of high-risk criteria and categories led to a better detection and primary prevention of patients at risk of a first cardiovascular event. Nonetheless, additional efforts are needed for a better inclusion of risk modifiers, especially specific to women, to improve risk stratification and direct primary prevention. Eventually, we discuss how these new guidelines implement PCSK9 inhibitors for very high-risk individuals and the evidence supporting new low-density lipoprotein cholesterol goals below, such as 55 and 40 mg/dL.

引用

页码：324 / 333

页数：10

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