Coagulation update: What's new in hemostasis testing?

被引：20

作者：

Favaloro, Emmanuel J. ^{[1
]}

Lippi, Giuseppe ^{[2
]}

机构：

[1] Westmead Hosp, Dept Haematol, WSAHS, ICPMR, Westmead, NSW 2145, Australia

[2] Univ Hosp Parma, Dept Pathol & Lab Med, Parma, Italy

来源：

THROMBOSIS RESEARCH | 2011年 / 127卷

关键词：

Hemostasis; Coagulation; Laboratory tests; Virchow's triad; PARTIAL THROMBOPLASTIN TIME; INCREASED THROMBIN GENERATION; VENOUS THROMBOEMBOLISM; CLINICAL UTILITY; FACTOR XA; MICROPARTICLES; THROMBOELASTOGRAPHY; STANDARDIZATION; DISEASE; CANCER;

D O I：

10.1016/S0049-3848(10)70148-1

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The current report provides a personal perspective summarising some interesting recent developments in hemostasis, as well as providing a brief glimpse into some possible imminent changes to come. We briefly review routine coagulation tests, and what changes may take place related to the new emerging anticoagulants. We also briefly review the old and new global tests of hemostasis, including thrombin generation and thromboelastography. Also briefly discussed within the diagnostics of bleeding and thrombotic disorders are the role of microparticles, the rise and fall of thrombophilia testing, the 'disappearance' of fibrinolysis pathway tests, and the absence of tests related to the endothelium, in part reflecting upon Virchow's triad. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：S13 / S16

页数：4

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