Novel insight into the pathobiology of abdominal aortic aneurysm and potential future treatment concepts

被引：42
作者：
Diehm, Nicolas
Dick, Florian
Schaffner, Thomas
Schmidli, Juerg
Kalka, Christoph
Di Santo, Stefano
Voelzmann, Jan
Baumgartner, Iris
机构：
[1] Univ Hosp Bern, Clin & Intervent Angiol, CH-3010 Bern, Switzerland
[2] Univ Hosp Bern, Swiss Cardiovasc Surg, Div Clin Intervent Angiol, CH-3010 Bern, Switzerland
[3] Univ Hosp Bern, Swiss Cardiovasc Surg, Dept Cardiovasc Surg, CH-3010 Bern, Switzerland
[4] Univ Hosp Bern, Swiss Cardiovasc Surg, Dept Pathol, CH-3010 Bern, Switzerland
来源：
PROGRESS IN CARDIOVASCULAR DISEASES | 2007年 / 50卷 / 03期
关键词：
NITRIC-OXIDE SYNTHASE; ANGIOTENSIN-II; RISK-FACTORS; VITAMIN-E; MATRIX METALLOPROTEINASES; SIMVASTATIN SUPPRESSES; PREVALENCE; EXPANSION; DISEASE; ATHEROSCLEROSIS;
D O I：
10.1016/j.pcad.2007.05.001
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The patient with abdominal aortic aneurysm (AAA) commonly is a nondiabetic, white man with a history of smoking. Moreover, AAA represents a leading cause of death in elderly men in Western countries. The purpose of this manuscript is to review current evidence as to the pathobiology of AAA as well as potential future drug targets to prevent progression of AAA. (C) 2007 Elsevier Inc. All rights reserved.
引用
收藏
页码：209 / 217
页数：9
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