A facile generation of enolates from silyl enol ethers by potassium ethoxide

被引：13

作者：

Yu, WS ^{[1
]}

Jin, ZD ^{[1
]}

机构：

[1] Univ Iowa, Coll Pharm, Div Med & Nat Prod Chem, Iowa City, IA 52242 USA

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 03期

关键词：

silyl enol ether; potassium alkyloxide; kinetic enolate; oxidation;

D O I：

10.1016/S0040-4039(00)01970-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Cyclic silyl enol ethers were successfully cleaved by EtOK to generate the corresponding enolates. Reactions with EtOK; were faster and the corresponding enolates could be trapped by electrophiles and oxidants to give the kinetic products exclusively. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：369 / 372

页数：4

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