Intergroup LEAP trial (S1612): A randomized phase 2/3 platform trial to test novel therapeutics in medically less fit older adults with acute myeloid leukemia

被引：13

作者：

Walter, Roland B. ^{[1
,2
]}

Michaelis, Laura C. ^{[3
]}

Othus, Megan ^{[4
]}

Uy, Geoffrey L. ^{[5
]}

Radich, Jerald P. ^{[1
,2
]}

Little, Richard F. ^{[6
]}

Hita, Sandi ^{[7
]}

Saini, Lalit ^{[8
]}

Foran, James M. ^{[9
]}

Gerds, Aaron T. ^{[10
]}

Klepin, Heidi D. ^{[11
]}

Hay, Annette E. ^{[12
]}

Assouline, Sarit ^{[13
]}

Lancet, Jeffrey E. ^{[14
]}

Couban, Stephen ^{[15
]}

Litzow, Mark R. ^{[16
]}

Stone, Richard M. ^{[17
]}

Erba, Harry P. ^{[18
]}

机构：

[1] Fred Hutchinson Canc Res Ctr, Clin Res Div, 1124 Columbia St, Seattle, WA 98104 USA

[2] Univ Washington, Dept Med, Seattle, WA USA

[3] Med Coll Wisconsin, Dept Hematol & Oncol, Milwaukee, WI 53226 USA

[4] Fred Hutchinson Canc Res Ctr, SWOG Stat Ctr, 1124 Columbia St, Seattle, WA 98104 USA

[5] Washington Univ, Sch Med, Dept Med, Div Oncol, St Louis, MO 63110 USA

[6] Natl Canc Inst, Canc Therapy Evaluat Program, Rockville, MD USA

[7] SWOG Operat, San Antonio, TX USA

[8] Univ Alberta, Dept Med, Edmonton, AB, Canada

[9] Mayo Clin, Div Hematol & Oncol, Jacksonville, FL 32224 USA

[10] Cleveland Clin, Taussig Canc Inst, Dept Hematol & Med Oncol, Cleveland, OH 44106 USA

[11] Wake Forest Univ, Wake Forest Baptist Comprehens Canc Ctr, Winston Salem, NC 27109 USA

[12] Queens Univ, Dept Med, Kingston, ON, Canada

[13] Jewish Gen Hosp, Montreal, PQ, Canada

[14] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA

[15] Dalhousie Univ, Div Hematol, Halifax, NS, Canada

[16] Mayo Clin, Dept Internal Med, Div Hematol, Rochester, MN USA

[17] Harvard Med Sch, Dana Farber Canc Inst, Adult Leukemia Program, Boston, MA USA

[18] Univ Alabama Birmingham, Div Hematol Oncol, North Pavil,Room 2556,1720 Second Ave South, Birmingham, AL 35294 USA

来源：

AMERICAN JOURNAL OF HEMATOLOGY | 2018年 / 93卷 / 02期

基金：

美国国家卫生研究院;

关键词：

LOW-DOSE CYTARABINE; SURVIVAL; CARE;

D O I：

10.1002/ajh.24980

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：E49 / E52

页数：4

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