Dapsone and sulfones in dermatology: Overview and update

被引：327
作者：
Zhu, YI [1 ]
Stiller, MJ [1 ]
机构：
[1] Columbia Presbyterian Med Ctr, Dept Dermatol, New York, NY 10032 USA
来源：
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 2001年 / 45卷 / 03期
关键词：
D O I：
10.1067/mjd.2001.114733
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
In their 60-year history, dapsone and the sulfones have been used as both antibacterial and antiinflammatory agents. Dapsone has been used successfully to treat a range of dermatologic disorders, most successfully those characterized by abnormal neutrophil and eosinophil accumulation. This article reviews and updates the chemistry, pharmacokinetics, clinical application, mechanism of action, adverse effects, and drug interactions of dapsone and the sulfones in dermatology.
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页码：420 / 434
页数：15
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