TNF and receptors in organ-specific autoimmune disease: multi-layered functioning mirrored in animal models

被引:34
作者
Kassiotis, G [1 ]
Kollias, G [1 ]
机构
[1] Biomed Sci Res Ctr Alexander Fleming, Inst Immunol, Varkiza 16602, Greece
关键词
D O I
10.1172/JCI13362
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
引用
收藏
页码:1507 / 1508
页数:2
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共 14 条
[1]   TNF neutralization in MS - Results of a randomized, placebo-controlled multicenter study [J].
Arnason, BGW ;
Jacobs, G ;
Hanlon, M ;
Clay, BH ;
Noronha, ABC ;
Auty, A ;
Davis, B ;
Nath, A ;
Bouchard, JP ;
Belanger, C ;
Gosselin, F ;
Thibault, M ;
Duquette, P ;
Bourgoin, P ;
DuBois, R ;
Girard, M ;
Ebers, GC ;
Rice, GPA ;
Vandervoort, MK ;
Francis, GS ;
Duncan, L ;
Lapierre, Y ;
Freedman, MS ;
Christie, SN ;
Rabinovitch, HE ;
Patry, D ;
Murphy, WF ;
Peters, S ;
McGuiness, SD ;
Murray, TJ ;
Bhan, V ;
Maxner, CE ;
Van Dorpe, R ;
Oger, JJ ;
Nelson, J ;
Morrison, W ;
Bogle, N ;
Beall, S ;
Vorobeychick, G ;
Hiltbrunner, AV ;
Bock, J ;
Habil ;
Lesslauer, W ;
Li, DKB ;
Paty, DW ;
Zhao, GJ .
NEUROLOGY, 1999, 53 (03) :457-465
[2]   Severe inflammatory arthritis and lymphadenopathy in the absence of TNF [J].
Campbell, IK ;
O'Donnell, K ;
Lawlor, KE ;
Wicks, IP .
JOURNAL OF CLINICAL INVESTIGATION, 2001, 107 (12) :1519-1527
[3]   Regulation of autoimmunity by proinflammatory cytokines [J].
Cope, AP .
CURRENT OPINION IN IMMUNOLOGY, 1998, 10 (06) :669-676
[4]  
Eugster HP, 1999, EUR J IMMUNOL, V29, P626, DOI 10.1002/(SICI)1521-4141(199902)29:02<626::AID-IMMU626>3.0.CO
[5]  
2-A
[6]   Anti-TNFα therapy of rheumatoid arthritis:: what have we learned? [J].
Feldmann, M ;
Maini, RN .
ANNUAL REVIEW OF IMMUNOLOGY, 2001, 19 :163-196
[7]   Local expression of transgene encoded TNF alpha in islets prevents autoimmune diabetes in nonobese diabetic (NOD) mice by preventing the development of auto-reactive islet-specific T cells [J].
Grewal, IS ;
Grewal, KD ;
Wong, FS ;
Picarella, DE ;
Janeway, CA ;
Flavell, RA .
JOURNAL OF EXPERIMENTAL MEDICINE, 1996, 184 (05) :1963-1974
[8]   The p55 TNF-α receptor plays a critical role in T cell alloreactivity [J].
Hill, GR ;
Teshima, T ;
Rebel, VI ;
Krijanovski, OI ;
Cooke, KR ;
Brinson, YS ;
Ferrara, JLM .
JOURNAL OF IMMUNOLOGY, 2000, 164 (02) :656-663
[9]   Uncoupling the proinflammatory from the immunosuppressive properties of tumor necrosis factor (TNF) at the p55 TNF receptor level: Implications for pathogenesis and therapy of autoimmune demyelination [J].
Kassiotis, G ;
Kollias, G .
JOURNAL OF EXPERIMENTAL MEDICINE, 2001, 193 (04) :427-434
[10]   On the role of tumor necrosis factor and receptors in models of multiorgan failure, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease [J].
Kollias, G ;
Douni, E ;
Kassiotis, G ;
Kontoyiannis, D .
IMMUNOLOGICAL REVIEWS, 1999, 169 :175-194