Site-specific integration ushers in a new era of precise CHO cell line engineering

被引：61
作者：
Hamaker, Nathaniel K. [1 ,2 ]
Lee, Kelvin H. [1 ,2 ]
机构：
[1] Delaware Biotechnol Inst, Newark, DE 19711 USA
[2] Univ Delaware, Chem & Biomol Engn, Newark, DE 19716 USA
来源：
CURRENT OPINION IN CHEMICAL ENGINEERING | 2018年 / 22卷
基金：
美国国家科学基金会;
关键词：
CASSETTE EXCHANGE RMCE; GENE INTEGRATION; EXPRESSION; ANTIBODY; GENOME; COEXPRESSION; CRISPR/CAS9; INSTABILITY; GENERATION;
D O I：
10.1016/j.coche.2018.09.011
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
[No abstract available]
引用
收藏
页码：152 / 160
页数：9
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