Synthesis of PEO-based block copolymers bearing cyclic hydrazide or carboxylic acid moieties and their applications as stabilizers for Fe3O4 nanoparticles

被引：3

作者：

Kim, Jinheung ^{[1
]}

Lee, Sangmi ^{[1
]}

Nam, Joo Hyeon ^{[1
]}

Cho, Young Jun ^{[1
]}

Kim, Joohoon ^{[1
]}

Lee, Jae Yeol ^{[1
]}

Kang, Ho-Jung ^{[1
]}

Kim, Sehoon ^{[2
]}

Kim, Hoon Tae ^{[3
]}

Park, Heung Mok ^{[3
]}

Kim, Jungahn ^{[1
]}

机构：

[1] Kyung Hee Univ, Dept Chem, Seoul 130701, South Korea

[2] KIST, Biomed Sci Ctr, Seoul 136791, South Korea

[3] Sogang Univ, Dept Chem Engn, Seoul 121742, South Korea

来源：

MACROMOLECULAR RESEARCH | 2011年 / 19卷 / 07期

关键词：

anionic block copolymerization; deimidation; poly(ethylene oxide-b-maleic acid); poly(ethylene oxide-b-maleic hydrazide); iron oxide nanoparticles; IRON-OXIDE NANOPARTICLES; N-SUBSTITUTED MALEIMIDE; MAGNETIC NANOPARTICLES; GABRIEL SYNTHESIS; ANIONIC-POLYMERIZATION; ING-MANSKE; HYDROLYSIS; COMPLEXES;

D O I：

10.1007/s13233-011-0716-0

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

In this paper, a useful synthetic method for poly(ethylene oxide)-based block copolymers and their applications for preparation of iron oxide nanoparticles were introduced. Poly(ethylene oxide-b-N-phenylmaleimide) was first synthesized by anionic block copolymerization of ethylene oxide and N-phenylmaleimide (N-PMI) using mixed alkali metal alkoxides via the sequential monomer addition technique in a mixture of benzene dimethylsulfoxide (DMSO)/tetrahydrofuran (THF) (30/5/6 similar to 20, v/v/v) at room temperature. Reductive deimidation of the resulting block copolymers under different reaction conditions using hydrazine monohydrate led to the formation of the corresponding water-soluble poly(ethylene oxide-b-maleic hydrazide) under acidic conditions and poly(ethylene oxideb-maleic acid) under basic conditions. Both were found to be very efficient stabilizers to prepare superparamagnetic iron oxide nanoparticles.

引用

页码：716 / 721

页数：6

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