Risk Factors for Incident Condyloma in a Multinational Cohort of Men: The HIM Study

被引:24
作者
Anic, Gabriella M. [2 ]
Lee, Ji-Hyun
Villa, Luisa L. [3 ]
Lazcano-Ponce, Eduardo [4 ]
Gage, Christine
Silva, Roberto Jose C. [5 ]
Baggio, Maria L. [3 ]
Quiterio, Manuel [4 ,6 ]
Salmeron, Jorge [4 ,6 ]
Papenfuss, Mary R.
Abrahamsen, Martha
Stockwell, Heather [2 ]
Rollison, Dana E.
Wu, Yougui [2 ]
Giuliano, Anna R. [1 ]
机构
[1] H Lee Moffitt Canc Ctr & Res Inst, MRC CANCONT, Dept Canc Epidemiol, Tampa, FL 33612 USA
[2] Univ S Florida, Coll Publ Hlth, Dept Epidemiol & Biostat, Tampa, FL USA
[3] Ludwig Inst Canc Res, Sao Paulo, Brazil
[4] Inst Nacl Salud Publ, Cuernavaca, Morelos, Mexico
[5] Ctr Referencia DST Aids, Sao Paulo, Brazil
[6] Inst Mexicano Seguro Social, Cuernavaca, Morelos, Mexico
基金
美国国家卫生研究院;
关键词
PAPILLOMAVIRUS TYPES 6; GENITAL WARTS; UNITED-STATES; NATURAL-HISTORY; HEALTH;
D O I
10.1093/infdis/jir851
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Identifying factors associated with condyloma are necessary for prevention efforts. Risk factors for incident condyloma were examined in a cohort of 2487 men from the United States, Brazil, and Mexico and were followed up every 6 months (median, 17.9 months). Factors strongly associated with condyloma were incident infection with human papillomavirus (HPV) types 6 and 11 (hazard ratio [HR], 12.42 [95% confidence interval {CI}, 3.78-40.77]), age (HR, 0.43 [95% CI, .26-.77]; 45-70 vs 18-30 years), high lifetime number of female partners (HR, 5.69 [95% CI, 1.80-17.97]; >= 21 vs 0 partners), and number of male partners (HR, 4.53 [95% CI, 1.68-12.20]; >= 3 vs 0 partners). The results suggest that HPV types 6 and 11 and recent sexual behavior are strongly associated with incident condyloma.
引用
收藏
页码:789 / 793
页数:5
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