Gene-altered islets for transplant: Giant leap or small step?

被引：6

作者：

Harlan, DM ^{[1
]}

机构：

[1] NIDDKD, Islet & Autoimmun Branch, NIH, US Dept HHS, Bethesda, MD 20892 USA

[2] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA

来源：

ENDOCRINOLOGY | 2004年 / 145卷 / 02期

关键词：

D O I：

10.1210/en.2003-1392

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：463 / 466

页数：4

共 51 条

[1] Pharmacological treatment of chronic diabetes by stimulating pancreatic β-cell regeneration with systemic co-administration of EGF and gastrin [J].

Brand, SJ ;

Tagerud, S ;

Lambert, P ;

Magill, SG ;

Tatarkiewicz, K ;

Doiron, K ;

Yan, YH .

PHARMACOLOGY & TOXICOLOGY, 2002, 91 (06) :414-420

[2] Portal venous pressure changes after sequential clinical islet transplantation [J].

Casey, JJ ;

Lakey, JRT ;

Ryan, EA ;

Paty, BW ;

Owen, R ;

O'Kelly, K ;

Nanji, S ;

Rajotte, RV ;

Korbutt, GS ;

Bigam, D ;

Kneteman, NN ;

Shapiro, AMJ .

TRANSPLANTATION, 2002, 74 (07) :913-915

[3] Overexpression of parathyroid hormone-related protein inhibits pancreatic β-cell death in vivo and in vitro [J].

Cebrian, A ;

García-Ocaña, A ;

Takane, KK ;

Sipula, D ;

Stewart, AF ;

Vasavada, RC .

DIABETES, 2002, 51 (10) :3003-3013

[4] Role of endogenous glucagon-like peptide-1 in islet regeneration after partial pancreatectomy [J].

De León, DD ;

Deng, SP ;

Madani, R ;

Ahima, RS ;

Drucker, DJ ;

Stoffers, DA .

DIABETES, 2003, 52 (02) :365-371

[5] Glucagon-like peptide 1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets [J].

Farilla, L ;

Bulotta, A ;

Hirshberg, B ;

Calzi, SL ;

Khoury, N ;

Noushmehr, H ;

Bertolotto, C ;

Di Mario, U ;

Harlan, DM ;

Perfetti, R .

ENDOCRINOLOGY, 2003, 144 (12) :5149-5158

[6]

Gaglia JL, 2001, CURR DIRECT AUTOIMMU, V4, P283

[7] Adenovirus-mediated hepatocyte growth factor expression in mouse islets improves pancreatic islet transplant performance and reduces beta cell death [J].

García-Ocaña, A ;

Takane, KK ;

Reddy, VT ;

Lopez-Talavera, JC ;

Vasavada, RC ;

Stewart, AF .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (01) :343-351

[8] Transgenic overexpression of hepatocyte growth factor in the β-cell markedly improves islet function and islet transplant outcomes in mice [J].

García-Ocaña, A ;

Vasavada, RC ;

Cebrian, A ;

Reddy, V ;

Takane, KK ;

López-Talavera, JC ;

Stewart, AF .

DIABETES, 2001, 50 (12) :2752-2762

[9] Hepatocyte growth factor overexpression in the islet of transgenic mice increases beta cell proliferation, enhances islet mass, and induces mild hypoglycemia [J].

Garcia-Ocaña, A ;

Takane, KK ;

Syed, MA ;

Philbrick, WM ;

Vasavada, RC ;

Stewart, AF .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (02) :1226-1232

[10]

Gelsinger Paul, 2002, Bull Med Ethics, P13

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