1-Sulfopyridinium chloride: Green and expeditious ionic liquid for the one-pot synthesis of fused 3,4-dihydropyrimidin-2(1H)-ones and thiones under solvent-free conditions

被引：15

作者：

Velpula, Ravibabu ^{[1
]}

Banothu, Janardhan ^{[1
]}

Gali, Rajitha ^{[1
]}

Deshineni, Rajitha ^{[2
]}

Bavantula, Rajitha ^{[1
]}

机构：

[1] Natl Inst Technol, Dept Chem, Warangal 506004, Andhra Pradesh, India

[2] Osmania Univ, Dept Chem, Hyderabad 500007, Andhra Pradesh, India

来源：

CHINESE CHEMICAL LETTERS | 2015年 / 26卷 / 03期

关键词：

Fused 3,4-dihydropyrimidin-2(1H)-ones; One-pot three component reaction; Solvent-free condition; 1-Sulfopyridinium chloride; Thiones; EFFICIENT SYNTHESIS; BIGINELLI-TYPE; SULFURIC-ACID; SULFAMIC ACID; CATALYST; 3,4-DIHYDROPYRIMIDIN-2-(1H)-ONES/THIONES; DIHYDROPYRIMIDINONES; PROTOCOL;

D O I：

10.1016/j.cclet.2014.11.030

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

1-Sulfopyridinium chloride portrayed as an efficient and recyclable ionic liquid for the synthesis of fused 3,4-dihydropyrimidin-2(1H)-ones and thiones via a modified Biginelli reaction involving one-pot three component condensation of 6-methoxy-1-tetralone, arylaldehydes and urea/thiourea under solvent-free conditions. Analytically pure products are formed within 10-20 min in excellent yields. (C) 2014 R. Bavantula. Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. All rights reserved.

引用

页码：309 / 312

页数：4

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