Synthesis and antimicrobial activities of 2-substituted 12H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidines, 3-ethoxycarbonyl-12H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine-2-one and ethyl 2-formylamino- and 2-acetylamino-4H-chromene-3-carboxylates

被引：35

作者：

El-Agrody, Ahmed M. ^{[1
]}

Sabry, Nermien M. ^{[2
]}

Motlaq, Shymaa S. ^{[2
]}

机构：

[1] King Khalid Univ, Dept Chem, Fac Sci, Abha 9004, Saudi Arabia

[2] King Khalid Univ, Dept Chem, Girls Coll Educ, Abha, Saudi Arabia

来源：

JOURNAL OF CHEMICAL RESEARCH | 2011年 / 02期

关键词：

4H-chromene; chromeno[2,3-d]pyrimidine; triazolo[1,5-c]pyrimidine; antimicrobial activities; ANTIINFLAMMATORY ACTIVITY; ANTILEISHMANIAL ACTIVITY; HETEROCYCLIC SYNTHESIS; DERIVATIVES; COUMARIN; 4-HYDROXYCOUMARIN; CHROMENE; SERIES;

D O I：

10.3184/174751911X12964930076728

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Preparation of 2-substituted 9-(diethylamino)-12-(4-chlorophenyl)-12H-chromenol3,2-e][1,2,4]triazolo[1,5-c]pyrimidines is reported. Furthermore, 3-benzylideneamino-5-(4-chlorophenyl)-8-(diethylamino)-4-imino-3,4-dihydro-5H-chromeno[2,3-d]pyrimidine, 3-ethoxycarbony1-12H-chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine-2-one, ethyl 2-formylamino- and 2-acetylamino-4H-chromene-3-carboxylates were prepared. Structures of these compounds were established on the basis of IR, UV, H-1 NMR, C-13 NMR and MS data. The new compounds were evaluated for antimicrobial activities.

引用

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页码：77 / 83

页数：7

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