Fatal H5N6 Avian Influenza Virus Infection in a Domestic Cat and Wild Birds in China

被引：75

作者：

Yu, Zhijun ^{[1
,2
]}

Gao, Xiaolong ^{[3
]}

Wang, Tiecheng ^{[1
,7
]}

Li, Yanbing ^{[3
]}

Li, Yongcheng ^{[4
]}

Xu, Yu ^{[4
]}

Chu, Dong ^{[4
]}

Sun, Heting ^{[4
]}

Wu, Changjiang ^{[4
]}

Li, Shengnan ^{[5
]}

Wang, Haijun ^{[5
]}

Li, Yuanguo ^{[6
]}

Xia, Zhiping ^{[1
,7
]}

Lin, Weishi ^{[1
,7
]}

Qian, Jun ^{[1
,7
]}

Chen, Hualan ^{[3
]}

Xia, Xianzhu ^{[1
,2
,7
,8
]}

Gao, Yuwei ^{[1
,7
,8
]}

机构：

[1] Acad Mil Med Sci, Res Ctr Wildlife Dis, Key Lab Jilin Prov Zoonosis Prevent & Control, Mil Vet Res Inst, Changchun 130122, Jilin Province, Peoples R China

[2] Chinese Acad Med Sci, Inst Lab Anim Sci, Beijing 100021, Peoples R China

[3] Chinese Acad Agr Sci, Harbin Vet Res Inst, State Key Lab Vet Biotechnol, Harbin 150001, Peoples R China

[4] State Forestry Adm, Gen Stn Surveillance Wildlife Dis & Wildlife, Shenyang 110034, Peoples R China

[5] Jilin Agr Univ, Coll Anim Sci & Vet Med, Changchun 130118, Peoples R China

[6] Gansu Agr Univ, Coll Vet Med, Lanzhou 730070, Peoples R China

[7] Chinese Acad Agr Sci, Changchun Vet Res Inst, Changchun 130122, Peoples R China

[8] Jiangsu Coinnovat Ctr Prevent & Control Important, Yangzhou 225009, Jiangsu, Peoples R China

来源：

SCIENTIFIC REPORTS | 2015年 / 5卷

关键词：

VIRULENCE;

D O I：

10.1038/srep10704

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

H5N6 avian influenza viruses (AIVs) may pose a potential human risk as suggested by the first documented naturally-acquired human H5N6 virus infection in 2014. Here, we report the first cases of fatal H5N6 avian influenza virus (AIV) infection in a domestic cat and wild birds. These cases followed human H5N6 infections in China and preceded an H5N6 outbreak in chickens. The extensive migration routes of wild birds may contribute to the geographic spread of H5N6 AIVs and pose a risk to humans and susceptible domesticated animals, and the H5N6 AIVs may spread from southern China to northern China by wild birds. Additional surveillance is required to better understand the threat of zoonotic transmission of AIVs.

引用

页数：5

共 11 条

[1]

[Anonymous], 2014, 3 HUMAN CASE H10N8 B

[2]

[Anonymous], 2014, 1 HUMAN CASE H5N6 BI

[3] Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection : a descriptive study [J].

Chen, HaiYing ;

Yuan, Hui ;

Gao, Rongbao ;

Zhang, Jinxiang ;

Wang, Dayan ;

Xiong, Ying ;

Fan, GuoYin ;

Yang, Fan ;

Li, Xiaodan ;

Zhou, Jianfang ;

Zou, Shumei ;

Yang, Lei ;

Chen, Tao ;

Dong, Libo ;

Bo, Hong ;

Zhao, Xiang ;

Zhang, Ye ;

Lan, Yu ;

Bai, Tian ;

Dong, Jie ;

Li, Qun ;

Wang, ShiWen ;

Zhang, YanPing ;

Li, Hui ;

Gong, Tian ;

Shi, Yong ;

Ni, Xiansheng ;

Li, Jianxiong ;

Zhou, Jun ;

Fan, Jiyi ;

Wu, Jingwen ;

Zhou, Xianfeng ;

Hu, Maohong ;

Wan, Jianguo ;

Yang, WeiZhong ;

Li, DeXin ;

Wu, Guizhen ;

Feng, ZiJian ;

Gao, George F. ;

Wang, Yu ;

Jin, Qi ;

Liu, Mingbin ;

Shu, Yuelong .

LANCET, 2014, 383 (9918) :714-721

[4] Environmental Factors Contributing to the Spread of H5N1 Avian Influenza in Mainland China [J].

Fang, Li-Qun ;

de Vlas, Sake J. ;

Liang, Song ;

Looman, Caspar W. N. ;

Gong, Peng ;

Xu, Bing ;

Yan, Lei ;

Yang, Hong ;

Richardus, Jan Hendrik ;

Cao, Wu-Chun .

PLOS ONE, 2008, 3 (05)

[5] Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus [J].

Gao, Rongbao ;

Cao, Bin ;

Hu, Yunwen ;

Feng, Zijian ;

Wang, Dayan ;

Hu, Wanfu ;

Chen, Jian ;

Jie, Zhijun ;

Qiu, Haibo ;

Xu, Ke ;

Xu, Xuewei ;

Lu, Hongzhou ;

Zhu, Wenfei ;

Gao, Zhancheng ;

Xiang, Nijuan ;

Shen, Yinzhong ;

He, Zebao ;

Gu, Yong ;

Zhang, Zhiyong ;

Yang, Yi ;

Zhao, Xiang ;

Zhou, Lei ;

Li, Xiaodan ;

Zou, Shumei ;

Zhang, Ye ;

Li, Xiyan ;

Yang, Lei ;

Guo, Junfeng ;

Dong, Jie ;

Li, Qun ;

Dong, Libo ;

Zhu, Yun ;

Bai, Tian ;

Wang, Shiwen ;

Hao, Pei ;

Yang, Weizhong ;

Zhang, Yanping ;

Han, Jun ;

Yu, Hongjie ;

Li, Dexin ;

Gao, George F. ;

Wu, Guizhen ;

Wang, Yu ;

Yuan, Zhenghong ;

Shu, Yuelong .

NEW ENGLAND JOURNAL OF MEDICINE, 2013, 368 (20) :1888-1897

[6] Neuraminidase Stalk Length and Additional Glycosylation of the Hemagglutinin Influence the Virulence of Influenza H5N1 Viruses for Mice [J].

Matsuoka, Yumiko ;

Swayne, David E. ;

Thomas, Colleen ;

Rameix-Welti, Marie-Anne ;

Naffakh, Nadia ;

Warnes, Christine ;

Altholtz, Melanie ;

Donis, Ruben ;

Subbarao, Kanta .

JOURNAL OF VIROLOGY, 2009, 83 (09) :4704-4708

[7] A Genetically Engineered Waterfowl Influenza Virus with a Deletion in the Stalk of the Neuraminidase Has Increased Virulence for Chickens [J].

Munier, S. ;

Larcher, T. ;

Cormier-Aline, F. ;

Soubieux, D. ;

Su, B. ;

Guigand, L. ;

Labrosse, B. ;

Cherel, Y. ;

Quere, P. ;

Marc, D. ;

Naffakh, N. .

JOURNAL OF VIROLOGY, 2010, 84 (02) :940-952

[8]

Office of the Ministry of Agriculture, 2014, OUTBR HIGHL PATH AV

[9] First Evidence of H10N8 Avian Influenza Virus Infections among Feral Dogs in Live Poultry Markets in Guangdong Province, China [J].

Su, Shuo ;

Qi, Wenbao ;

Zhou, Pei ;

Xiao, Chencheng ;

Yan, Zhongshan ;

Cui, Jin ;

Jia, Kun ;

Zhang, Guihong ;

Gray, Gregory C. ;

Liao, Ming ;

Li, Shoujun .

CLINICAL INFECTIOUS DISEASES, 2014, 59 (05)

[10] Novel Avian Influenza A(H7N9) Virus in Tree Sparrow, Shanghai, China, 2013 [J].

Zhao, Baihui ;

Zhang, Xi ;

Zhu, Wenfei ;

Teng, Zheng ;

Yu, Xuelian ;

Gao, Ye ;

Wu, Di ;

Pei, Enle ;

Yuan, Zhengan ;

Yang, Lei ;

Wang, Dayan ;

Shu, Yuelong ;

Wu, Fan .

EMERGING INFECTIOUS DISEASES, 2014, 20 (05) :850-853

← 1 2 →