The Osteoarticular Infection in a Pediatric Emergency Setting A Challenging Diagnosis

被引:11
作者
Boccuzzi, Elena [1 ]
Buonsenso, Danilo [2 ,3 ]
Ferro, Valentina [1 ]
Raucci, Umberto [1 ]
Reale, Antonino [1 ]
Piga, Simone [4 ]
Deriu, Daniele [5 ]
Krzysztofiak, Andrzej [5 ]
机构
[1] Bambino Gesu Pediat Hosp, Pediat Emergency Dept, Piazza St Onofrio 4, I-00165 Rome, Italy
[2] Fdn Policlin Univ A Gemelli, Dept Woman & Child Hlth & Publ Hlth, IRCCS, Rome, Italy
[3] Univ Cattolica Sacro Cuore, Rome, Italy
[4] Bambino Gesu Pediat Hosp, IRCCS, Clin Epidemiol Unit, Med Direct, Rome, Italy
[5] Bambino Gesu Pediat Hosp, IRCCS, Acad Dept, Pediat & Infect Dis Unit, Rome, Italy
关键词
osteoarticular infection; osteomyelitis; septic arthritis; C-REACTIVE PROTEIN; ACUTE HEMATOGENOUS OSTEOMYELITIS; ERYTHROCYTE SEDIMENTATION-RATE; BLOOD-CELL COUNT; BONE;
D O I
10.1097/PEC.0000000000002045
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
t Objectives: The study aimed to evaluate the emergency department (ED) presentation of children with a diagnosis of osteomyelitis, septic arthritis, or both. Methods: A retrospective single-center study was conducted on all children aged between 1 month and 18 years evaluated in the ED over a 7-year period and having a final diagnosis of osteoarticular infection. One hundred seventeen patients were enrolled. Results: Only 39.3% of patients were admitted after the first evaluation, and only 45.3% had a proper diagnosis of admission. Pain was the only symptom reported by all. White cell count, C-reactive protein level, and erythrocytes sedimentation rate were normal in 49.5%, 21.4%, and 17.1% of children, respectively. X-ray findings were unremarkable in 48% of cases. Clinical and bone structural sequelae were described in 19.23% and 56.86% of all cases. No statistically significant differences were found among osteomyelitis, arthritis, and the combination of both regarding all considered variables, except for structural outcomes resulting more significant in the third group. Significant differences were evident in clinical manifestations, blood examinations, and findings of osteolysis between patients diagnosed within and after 1 week since the disease onset. Finally, questionable differences between white blood cells and C-reactive protein level were found among patients younger than 5 years and older ones, whereas a history of trauma was more often reported in the second group. Conclusions: The difficulty in recognizing osteoarticular infection in a pediatric ED can be due to the possible lack of the classic signs and symptoms, and the absence of specific laboratory and radiologic findings.
引用
收藏
页码:E108 / E114
页数:7
相关论文
共 23 条
[1]   Presentation and Investigation of Pediatric Bone and Joint Infections in the Pediatric Emergency Department [J].
Akinkugbe, Olugbenga ;
Stewart, Charles ;
McKenna, Caoimhe .
PEDIATRIC EMERGENCY CARE, 2019, 35 (10) :700-704
[2]   Osteoarticular Infections in Children [J].
Arnold, John C. ;
Bradley, John S. .
INFECTIOUS DISEASE CLINICS OF NORTH AMERICA, 2015, 29 (03) :557-+
[3]   Changing patterns of acute hematogenous osteomyelitis and septic arthritis - Emergence of community-associated methicillin-resistant Staphylococcus aureus [J].
Arnold, Sandra R. ;
Elias, David ;
Buckingham, Steven C. ;
Thomas, Eddie D. ;
Novais, Eduardo ;
Arkader, Alexandre ;
Howard, Cassandra .
JOURNAL OF PEDIATRIC ORTHOPAEDICS, 2006, 26 (06) :703-708
[4]  
Azouz EM., 1994, CURR ORTHOPAED, V8, P226
[5]   Update on imaging of orthopedic infections [J].
Boutin, RD ;
Brossmann, J ;
Sartoris, DJ ;
Reilly, D ;
Resnick, D .
ORTHOPEDIC CLINICS OF NORTH AMERICA, 1998, 29 (01) :41-+
[6]   DIFFERENTIATING OSTEOARTICULAR INFECTIONS CAUSED BY KINGELLA KINGAE FROM THOSE DUE TO TYPICAL PATHOGENS IN YOUNG CHILDREN [J].
Ceroni, Dimitri ;
Cherkaoui, Abdessalam ;
Combescure, Christophe ;
Francois, Patrice ;
Kaelin, Andre ;
Schrenzel, Jacques .
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2011, 30 (10) :906-909
[7]   Risk factors associated with complications/sequelae of acute and subacute haematogenous osteomyelitis: an Italian multicenter study [J].
Chiappini, Elena ;
Krzysztofiak, Andrzej ;
Bozzola, Elena ;
Gabiano, Clara ;
Esposito, Susanna ;
Lo Vecchio, Andrea ;
Govoni, Maria Rita ;
Vallongo, Cristina ;
Dodi, Icilio ;
Castagnola, Elio ;
Rossi, Nadia ;
Valentini, Piero ;
Cardinale, Fabio ;
Salvini, Filippo ;
Bona, Gianni ;
Bossi, Grazia ;
Olivieri, Alma Nunzia ;
Russo, Fiorella ;
Fossali, Emilio ;
Bottone, Gabriella ;
Dellepiane, Marta ;
De Martino, Maurizio ;
Villani, Alberto ;
Galli, Luisa .
EXPERT REVIEW OF ANTI-INFECTIVE THERAPY, 2018, 16 (04) :351-358
[8]   A Case of Acute Osteomyelitis: An Update on Diagnosis and Treatment [J].
Chiappini, Elena ;
Mastrangelo, Greta ;
Lazzeri, Simone .
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2016, 13 (06)
[9]   Haematogenous acute and subacute paediatric osteomyelitis A SYSTEMATIC REVIEW OF THE LITERATURE [J].
Dartnell, J. ;
Ramachandran, M. ;
Katchburian, M. .
JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 2012, 94B (05) :584-595
[10]   Bone and joint infections in children [J].
Gutierrez, K .
PEDIATRIC CLINICS OF NORTH AMERICA, 2005, 52 (03) :779-+