Using an integrative genome annotation pipeline (iGAP) for proteome-wide protein structure and functional domain assignment, we analyzed all the proteins of Arabidopsis thaliana. Three-dimensional structures at the level of the domain are assigned by fold recognition and threading based on a novel fold library that extends common domain classifications. iGAP is being applied to proteins from all available proteomes as part of a comparative proteomics resource. The database is accessible from the web.
机构:Iowa State Univ, Dept Genet Dev & Cell Biol, Roy J Carver Colab 1035A, Ames, IA 50011 USA
Peterson-Burch, BD
Nettleton, D
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机构:Iowa State Univ, Dept Genet Dev & Cell Biol, Roy J Carver Colab 1035A, Ames, IA 50011 USA
Nettleton, D
Voytas, DF
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Iowa State Univ, Dept Genet Dev & Cell Biol, Roy J Carver Colab 1035A, Ames, IA 50011 USAIowa State Univ, Dept Genet Dev & Cell Biol, Roy J Carver Colab 1035A, Ames, IA 50011 USA