Assessment of sentinel lymph node biopsy in patients receiving neoadjuvant chemotherapy in breast cancer: before or after?

被引:4
作者
Coutant, C. [1 ,2 ]
Jankowski, C. [1 ,2 ]
Portha, H. [1 ]
Barranger, E. [3 ]
机构
[1] Ctr Lutte Canc Georges Francois Leclerc CGFL, Dept Chirurg Oncol, 1 Rue Prof Marion, F-21000 Dijon, France
[2] Univ Bourgogne, UFR Sci Sante, 7 Blvd Jeanne dArc, F-21000 Dijon, France
[3] Ctr Antoine Lacassagne, Pole Chirurg Oncol Gen Gynecol & Mammaire, 33 Ave Valombrose, F-06189 Nice 2, France
来源
GYNECOLOGIE OBSTETRIQUE & FERTILITE | 2016年 / 44卷 / 06期
关键词
Breast cancer; Preoperative chemotherapy; Sentinel lymph node; SURGICAL ADJUVANT BREAST; ACOSOG Z1071 ALLIANCE; PROJECT PROTOCOL B-27; PREOPERATIVE CHEMOTHERAPY; AXILLARY DISSECTION; AMERICAN-SOCIETY; META-ANALYSIS; SURGERY; TRIAL; IDENTIFICATION;
D O I
10.1016/j.gyobfe.2016.04.010
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
The main goal of preoperative chemotherapy is to reduce the size of the tumor and allow conservative treatment. Neoadjuvant treatment can affect axillary status with a downstaging in one third of the cases. For these patients, the benefit of axillary node dissection is questioned and the sentinel node biopsy (SLNB) seems to be a relevant option. However, the timing of performing SLNB is still debated especially for clinical negative patients with negative axillary ultrasound before preoperative chemotherapy. For axillary positive nodes proved by biopsy/cytology before preoperative chemotherapy, SLNB can be an option if there is a good clinical and radiological response. (C) 2016 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:345 / 349
页数:5
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