PGxKnow: a pharmacogenomics educational HoloLens application of augmented reality and artificial intelligence

被引：23

作者：

Roosan, Don ^{[1
]}

Chok, Jay ^{[2
]}

Baskys, Andrius ^{[3
]}

Roosan, Moom R. ^{[4
]}

机构：

[1] Western Univ Hlth Sci, Coll Pharm, Dept Pharm Practice & Adm, 309 E 2nd St, Pomona, CA 91766 USA

[2] Claremont Coll, Sch Appl Life Sci, Keck Grad Inst, Claremont, CA 91711 USA

[3] Western Univ Hlth Sci, Coll Grad Biomed Sci, 309 E 2nd St, Pomona, CA 91766 USA

[4] Chapman Univ, Sch Pharm, Dept Pharm Practice, 9401 Jeronimo Rd, Irvine, CA 92618 USA

来源：

PHARMACOGENOMICS | 2022年 / 23卷 / 04期

关键词：

artificial intelligence; augmented reality; educational application; HoloLens; interactive learning; PGxKnow; pharmacogenomics; MODEL; TASK;

D O I：

10.2217/pgs-2021-0120

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Aim: To develop and assess an augmented reality tool for pharmacogenomics (PGx) education based on artificial intelligence. Materials & methods: A HoloLens application was developed using feedback from three clinical PGx-trained pharmacists. 15 Participants independently reviewed the application and assessed usability using the system usability scale (SUS). Results & conclusion: Eighteen different frames were developed. Each video module was 2-3 min for the education. The application included textual information and 3D structures of PGx concepts. The mean SUS score for 15 participants (11 pharmacy students and four pharmacists) was 83, with a standard deviation of 6.6. Results suggest that PGxKnow has the potential to bridge the gap in PGx education, further widespread utilization of PGx and boost its impact on precision medicine.

引用

页码：235 / 245

页数：12

共 50 条

[1] A deep convolutional neural network model to classify heartbeats [J].

Acharya, U. Rajendra ;

Oh, Shu Lih ;

Hagiwara, Yuki ;

Tan, Jen Hong ;

Adam, Muhammad ;

Gertych, Arkadiusz ;

Tan, Ru San .

COMPUTERS IN BIOLOGY AND MEDICINE, 2017, 89 :389-396

[2]

Albawi S, 2017, I C ENG TECHNOL

[3]

[Anonymous], 2018, P NIME

[4] Functional analysis of genetic variants in the human concentrative nucleoside transporter 3 (CNT3; SLC28A3) [J].

Badagnani, I ;

Chan, W ;

Castro, RA ;

Brett, CM ;

Huang, CC ;

Stryke, D ;

Kawamoto, M ;

Johns, SJ ;

Ferrin, TE ;

Carlson, EJ ;

Burchard, EG ;

Giacomini, KM .

PHARMACOGENOMICS JOURNAL, 2005, 5 (03) :157-165

[5]

Bangor A, 2009, J USABILITY STUD, V4, P114

[6] Augmented Reality in education-cases, places and potentials [J].

Bower, Matt ;

Howe, Cathie ;

McCredie, Nerida ;

Robinson, Austin ;

Grover, David .

EDUCATIONAL MEDIA INTERNATIONAL, 2014, 51 (01) :1-15

[7] Augmented Reality Integrated Simulation Education in Health Care [J].

Carlson, Kasey J. ;

Gagnon, David J. .

CLINICAL SIMULATION IN NURSING, 2016, 12 (04) :123-127

[8]

Chen C., 2019, ournal of Educational Technology Development and Exchange (JETDE), V12, DOI DOI 10.18785/JETDE.1201.02

[9] An Augmented Reality Question Answering System Based on Ensemble Neural Networks [J].

Chen, Chi-Hua ;

Wu, Chen-Ling ;

Lo, Chi-Chun ;

Hwang, Feng-Jang .

IEEE ACCESS, 2017, 5 :17425-17435

[10] Virtual Pharmacist: A Platform for Pharmacogenomics [J].

Cheng, Ronghai ;

Leung, Ross Ka-Kit ;

Chen, Yao ;

Pan, Yidan ;

Tong, Yin ;

Li, Zhoufang ;

Ning, Luwen ;

Ling, Xuefeng B. ;

He, Jiankui .

PLOS ONE, 2015, 10 (10)

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