A polymorphism in DMRT1 is associated with asthma in boys only and affects promoter activity by allele-specific transcription factor binding

被引:0
作者
Schieck, Maximilian [1 ]
Schouten, Jan P. [17 ]
Suttner, Kathrin [1 ,2 ,3 ]
Michel, Sven [1 ]
Rosenstiel, Philip [4 ]
Klopp, Normann [5 ,6 ]
Illig, Thomas [5 ,6 ]
Genuneit, Jon [7 ]
Vogelberg, Christian [8 ]
von Berg, Andrea [9 ]
Bufe, Albrecht [10 ]
Heinzmann, Andrea [11 ]
Frischer, Thomas [12 ]
Laub, Otto [13 ]
Rietschel, Ernst [14 ]
Simma, Burkhard [15 ]
von Mutius, Erika [16 ]
Boezen, Marike [17 ]
Kabesch, Michael [1 ]
机构
[1] Hannover Med Sch, Dept Pediat Pneumol Allergy & Neonatol, Hannover, Germany
[2] Tech Univ Munich, Ctr Allergy & Environm, Munich, Germany
[3] Helmholtz Ctr, Munich, Germany
[4] Christian Albrechts Univ Kiel, Inst Clin Mol Biol, Kiel, Germany
[5] Helmholtz Zentrum Munich, Res Unit Mol Epidemiol, Neuherberg, Germany
[6] Hannover Med Sch, Hannover Unified Biobank, Hannover, Germany
[7] Ulm Univ, Inst Epidemiol & Med Biometry, Ulm, Germany
[8] Tech Univ, Univ Childrens Hosp, Dresden, Germany
[9] Marien Hosp, Childrens Dept, Res Inst Prevent Allerg Dis, Wesel, Germany
[10] Ruhr Univ, Dept Expt Pneumol, Bochum, Germany
[11] Albert Ludwigs Univ, Univ Childrens Hosp, Freiburg, Germany
[12] Univ Childrens Hosp, Vienna, Austria
[13] Kinder & Jugendarztpraxis Laub, Rosenheim, Germany
[14] Univ Cologne, Univ Childrens Hosp, Cologne, Germany
[15] Landeskrankenhaus, Univ Teaching Hosp, Childrens Dept, Feldkirch, Austria
[16] Ludwig Maximilians Univ Munchen, Univ Childrens Hosp, Munich, Germany
[17] Univ Groningen, Univ Med Ctr Groningen, Dept Epidemiol, Groningen, Netherlands
关键词
Asthma; -; mechanism; Genetics; Functional genomics;
D O I
暂无
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
2925
引用
收藏
页数:2
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