Cardiovascular Control During Exercise: The Connectivity of Skeletal Muscle Afferents to the Brain

被引：19
作者：
Teixeira, Andre L. [1 ]
Fernandes, Igor A. [1 ]
Vianna, Lauro C. [1 ]
机构：
[1] Univ Brasilia, Fac Phys Educ, NeuroVASQ Integrat Physiol Lab, Darcy Ribeiro Campus, BR-70910900 Brasilia, DF, Brazil
来源：
EXERCISE AND SPORT SCIENCES REVIEWS | 2020年 / 48卷 / 02期
关键词：
exercise pressor reflex; metaboreflex; mechanoreflex; blood pressure; heart rate; GABA; OPIOID RECEPTORS ATTENUATE; SPINAL-CORD CONTRIBUTES; BLOOD-PRESSURE RESPONSE; GROUP-IV AFFERENTS; HEART-RATE; STATIC EXERCISE; GROUP-III; SYMPATHETIC ACTIVATION; TRPV1; RECEPTOR; REFLEX;
D O I：
10.1249/JES.0000000000000218
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
The exercise pressor reflex (EPR) is engaged upon the activation of group III/IV skeletal muscle afferents and is one of the principal mediators of cardiovascular responses to exercise. This review explores the hypothesis that afferent signals from EPR communicate via GABAergic contacts within the brain stem to evoke parasympathetic withdrawal and sympathoexcitation to increase cardiac output, peripheral resistance, and blood pressure during exercise.
引用
收藏
页码：83 / 91
页数：9
相关论文
共 78 条
  • [1] Intrathecal blockade of both NMDA and non-NMDA receptors attenuates the exercise pressor reflex in cats
    Adreani, CM
    Hill, JM
    Kaufman, MP
    [J]. JOURNAL OF APPLIED PHYSIOLOGY, 1996, 80 (01) : 315 - 322
  • [2] OBSERVATIONS IN MAN ON A PULSE-ACCELERATING REFLEX FROM THE VOLUNTARY MUSCLES OF THE LEGS
    Alam, M.
    Smirk, F. H.
    [J]. JOURNAL OF PHYSIOLOGY-LONDON, 1938, 92 (02): : 167 - 177
  • [3] Observations in man upon a blood pressure raising reflex arising from the voluntary muscles
    Alam, M
    Smirk, FH
    [J]. JOURNAL OF PHYSIOLOGY-LONDON, 1937, 89 (04): : 372 - 383
  • [4] Alam M, 1938, CLIN SCI, V3, P247
  • [5] Group III/IV muscle afferents impair limb blood in patients with chronic heart failure
    Amann, Markus
    Venturelli, Massimo
    Ives, Stephen J.
    Morgan, David E.
    Gmelch, Benjamin
    Witman, Melissa A. H.
    Groot, H. Jonathan
    Wray, D. Walter
    Stehlik, Josef
    Richardson, Russell S.
    [J]. INTERNATIONAL JOURNAL OF CARDIOLOGY, 2014, 174 (02) : 368 - 375
  • [6] Group III and IV muscle afferents contribute to ventilatory and cardiovascular response to rhythmic exercise in humans
    Amann, Markus
    Blain, Gregory M.
    Proctor, Lester T.
    Sebranek, Joshua J.
    Pegelow, David F.
    Dempsey, Jerome A.
    [J]. JOURNAL OF APPLIED PHYSIOLOGY, 2010, 109 (04) : 966 - 976
  • [7] Carotid baroreflex function at the onset of cycling in men
    Barbosa, Thales C.
    Vianna, Lauro C.
    Hashimoto, Takeshi
    Petersen, Lonnie G.
    Olesen, Niels D.
    Tsukamoto, Hayato
    Sorensen, Henrik
    Ogoh, Shigehiko
    Nobrega, Antonio C. L.
    Secher, Niels H.
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 2016, 311 (05) : R870 - R878
  • [8] Intrathecal fentanyl abolishes the exaggerated blood pressure response to cycling in hypertensive men
    Barbosa, Thales C.
    Vianna, Lauro C.
    Fernandes, Igor A.
    Prodel, Eliza
    Rocha, Helena N. M.
    Garcia, Vinicius P.
    Rocha, Natalia G.
    Secher, Niels H.
    Nobrega, Antonio C. L.
    [J]. JOURNAL OF PHYSIOLOGY-LONDON, 2016, 594 (03): : 715 - 725
  • [9] Oscillatory blood pressure response to the onset of cycling exercise in men: role of group III/IV muscle afferents
    Barbosa, Thales C.
    Fernandes, Igor A.
    Magalhaes-, Nisval, Jr.
    Cavalcanti, Ismar L.
    Secher, Niels H.
    Nobrega, Antonio C. L.
    Vianna, Lauro C.
    [J]. EXPERIMENTAL PHYSIOLOGY, 2015, 100 (03) : 302 - 311
  • [10] Acid-sensing ion channels blockade attenuates pressor and sympathetic responses to skeletal muscle metaboreflex activation in humans
    Campos, Monique O.
    Mansur, Daniel E.
    Mattos, Joao D.
    Paiva, Adrielle C. S.
    Videira, Rogerio L. R.
    Macefield, Vaughan G.
    da Nobrega, Antonio C. L.
    Fernandes, Igor A.
    [J]. JOURNAL OF APPLIED PHYSIOLOGY, 2019, 127 (05) : 1491 - 1501
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