A Bottom-Up Cell Modeling Strategy Using Broadband Microwave and Millimeter Wave Dielectric Spectroscopy

In this paper we introduce a bottom-up microwave and millimeter wave modeling strategy' for membrane bound biological systems. The approach is based on the stepwise integration of bulk liquid and membrane dielectric spectroscopy data into 3D biophysical models that are amenable to efficient electromagnetic computation. The purpose of this modeling effort is to develop more understanding of microwave electric field interactions with biological systems from a molecular biology point of view. The proposed strategy allows the systematic study of dielectric interactions within increasingly more complex membrane bound biological systems.