Clinical and radiological features of invasive pulmonary aspergillosis in transplant recipients and neutropenic patients

被引：73

作者：

Park, S. Y. ^{[1
]}

Kim, S. -H. ^{[1
]}

Choi, S. -H. ^{[1
]}

Sung, H. ^{[2
]}

Kim, M. -N. ^{[2
]}

Woo, J. H. ^{[1
]}

Kim, Y. S. ^{[1
]}

Park, S. -K. ^{[3
]}

Lee, J-H. ^{[4
]}

Lee, K. -H. ^{[4
]}

Lee, S. -G. ^{[5
]}

Hans, D. J. ^{[5
]}

Lee, S-O ^{[1
]}

机构：

[1] Univ Ulsan, Coll Med, Asan Med Ctr, Dept Infect Dis, Seoul, South Korea

[2] Univ Ulsan, Coll Med, Asan Med Ctr, Dept Lab Med, Seoul, South Korea

[3] Univ Ulsan, Coll Med, Asan Med Ctr, Dept Nephrol, Seoul, South Korea

[4] Univ Ulsan, Coll Med, Asan Med Ctr, Dept Hematol, Seoul, South Korea

[5] Univ Ulsan, Coll Med, Asan Med Ctr, Dept Surg, Seoul, South Korea

来源：

TRANSPLANT INFECTIOUS DISEASE | 2010年 / 12卷 / 04期

关键词：

IMMUNOCOMPROMISED PATIENTS; PATHOLOGICAL FINDINGS; COMPUTED-TOMOGRAPHY; FUNGAL-INFECTIONS; GALACTOMANNAN; GRANULOCYTOPENIA; CONSENSUS; CANCER; CT;

D O I：

10.1111/j.1399-3062.2010.00499.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Invasive pulmonary aspergillosis (IPA) is an important cause of mortality in transplant recipients and in patients with neutropenia. Although IPA has been studied extensively in neutropenic patients, there are limited data on IPA in recipients of solid organ transplants (SOTs).We compared the clinical features and radiologic findings of 27 SOT recipients with IPA with those of 35 neutropenic patients with IPA. The SOT recipients were more likely than neutropenic patients to show peribronchial consolidation (31% vs. 7%; P = 0.03) or ground-glass opacity (38% vs. 7%; P = 0.007) and less likely to have fever (22% vs. 80%; P< 0.001), macro-nodules (35% vs. 67%; P = 0.02), mass-like consolidation (27% vs. 67%; P = 0.004), halo signs (8% vs. 56%; P < 0.001), or air-crescent signs (0% vs. 22%; P = 0.01).

引用

页码：309 / 315

页数：7

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