sTREM-1 is a specific biomarker of TREM-1 pathway activation

被引:43
作者
Jolly, Lucie [1 ]
Carrasco, Kevin [1 ]
Salcedo-Magguilli, Margarita [1 ]
Garaud, Jean-Jacques [1 ]
Lambden, Simon [1 ]
van der Poll, Tom [2 ]
Mebazaa, Alexandre [3 ,4 ]
Laterre, Pierre-Francois [5 ]
Gibot, Sebastien [6 ,7 ]
Boufenzer, Amir [1 ]
Derive, Marc [1 ]
机构
[1] Inotrem, Vandoeuvre Les Nancy, France
[2] Univ Amsterdam, Amsterdam Univ Med Ctr, Div Infect Dis, Amsterdam, Netherlands
[3] St Louis Lariboisiere Fernand Widal Univ Hosp, AP HP, Intens Care Unit, Paris, France
[4] Univ Paris, INSERM, MASCOT, Paris, France
[5] Catholic Univ Louvain, Intens Care Unit, Louvain La Neuve, Belgium
[6] CHRU Nancy, Intens Care Unit, Nancy, France
[7] Univ Lorraine, Nancy, France
关键词
ECTODOMAIN;
D O I
10.1038/s41423-021-00733-5
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
[No abstract available]
引用
收藏
页码:2054 / 2056
页数:3
相关论文
共 7 条
[1]   Cutting edge: Inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes [J].
Bouchon, A ;
Dietrich, J ;
Colonna, M .
JOURNAL OF IMMUNOLOGY, 2000, 164 (10) :4991-4995
[2]   Potentiation of NETs release is novel characteristic of TREM-1 activation and the pharmacological inhibition of TREM-1 could prevent from the deleterious consequences of NETs release in sepsis [J].
Boufenzer, Amir ;
Carrasco, Kevin ;
Jolly, Lucie ;
Brustolin, Benjamin ;
Di-Pillo, Elisa ;
Derive, Marc ;
Gibot, Sebastien .
CELLULAR & MOLECULAR IMMUNOLOGY, 2021, 18 (02) :452-460
[3]   TREM-1 multimerization is essential for its activation on monocytes and neutrophils [J].
Carrasco, Kevin ;
Boufenzer, Amir ;
Jolly, Lucie ;
Le Cordier, Helene ;
Wang, Guanbo ;
Heck, Albert J. R. ;
Cerwenka, Adelheid ;
Vinolo, Emilie ;
Nazabal, Alexis ;
Kriznik, Alexandre ;
Launay, Pierre ;
Gibot, Sebastien ;
Derive, Marc .
CELLULAR & MOLECULAR IMMUNOLOGY, 2019, 16 (05) :460-472
[4]   Nangibotide in patients with septic shock: a Phase 2a randomized controlled clinical trial [J].
Francois, Bruno ;
Wittebole, Xavier ;
Ferrer, Ricard ;
Mira, Jean-Paul ;
Dugernier, Thierry ;
Gibot, Sebastien ;
Derive, Marc ;
Olivier, Aurelie ;
Cuvier, Valerie ;
Witte, Stephan ;
Pickkers, Peter ;
Vandenhende, Francois ;
Garaud, Jean-Jacques ;
Sanchez, Miguel ;
Salcedo-Magguilli, Margarita ;
Laterre, Pierre-Francois .
INTENSIVE CARE MEDICINE, 2020, 46 (07) :1425-1437
[5]   Metalloproteinases shed TREM-1 ectodomain from lipopolysaccharide-stimulated human monocytes [J].
Gomez-Pina, Vanesa ;
Soares-Schanoski, Alessandra ;
Rodriguez-Rojas, Alexandro ;
del Fresno, Carlos ;
Garcia, Felipe ;
Vallejo-Cremades, Maria Teresa ;
Fernandez-Ruiz, Irene ;
Arnalich, Francisco ;
Fuentes-Prior, Pablo ;
Lopez-Collazo, Eduardo .
JOURNAL OF IMMUNOLOGY, 2007, 179 (06) :4065-4073
[6]   Targeted endothelial gene deletion of triggering receptor expressed on myeloid cells-1 protects mice during septic shock [J].
Jolly, Lucie ;
Carrasco, Kevin ;
Derive, Marc ;
Lemarie, Jeremie ;
Boufenzer, Amir ;
Gibot, Sebastien .
CARDIOVASCULAR RESEARCH, 2018, 114 (06) :907-918
[7]   Reversal of TREM-1 ectodomain shedding and improved bacterial clearance by intranasal metalloproteinase inhibitors [J].
Weiss, G. ;
Lai, C. ;
Fife, M. E. ;
Grabiec, A. M. ;
Tildy, B. ;
Snelgrove, R. J. ;
Xin, G. ;
Lloyd, C. M. ;
Hussell, T. .
MUCOSAL IMMUNOLOGY, 2017, 10 (04) :1021-1030