We present a simple method to control the position of ellipsoidal magnetic particles in microchannel Poiseuille flow at low Reynolds number using a static uniform magnetic field. The magnetic field is utilized to pin the particle orientation, and the hydrodynamic interactions between ellipsoids and channel walls allow control of the transverse position of the particles. We employ a far-field hydrodynamic theory and simulations using the boundary element method and Brownian dynamics to show how magnetic particles can be focused and segregated by size and shape. This is of importance for particle manipulation in lab-on-a-chip devices.
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Massachusetts Gen Hosp, Ctr Engn Med & Surg Serv, BioMEMS Resource Ctr, Shriners Hosp Children, Boston, MA 02114 USA
Harvard Univ, Sch Med, Boston, MA 02114 USAMassachusetts Gen Hosp, Ctr Engn Med & Surg Serv, BioMEMS Resource Ctr, Shriners Hosp Children, Boston, MA 02114 USA
Hsu, Chia-Hsien
Di Carlo, Dino
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Massachusetts Gen Hosp, Ctr Engn Med & Surg Serv, BioMEMS Resource Ctr, Shriners Hosp Children, Boston, MA 02114 USA
Harvard Univ, Sch Med, Boston, MA 02114 USAMassachusetts Gen Hosp, Ctr Engn Med & Surg Serv, BioMEMS Resource Ctr, Shriners Hosp Children, Boston, MA 02114 USA
Di Carlo, Dino
Chen, Chihchen
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Massachusetts Gen Hosp, Ctr Engn Med & Surg Serv, BioMEMS Resource Ctr, Shriners Hosp Children, Boston, MA 02114 USA
Harvard Univ, Sch Med, Boston, MA 02114 USAMassachusetts Gen Hosp, Ctr Engn Med & Surg Serv, BioMEMS Resource Ctr, Shriners Hosp Children, Boston, MA 02114 USA
Chen, Chihchen
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Irimia, Daniel
Toner, Mehmet
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Massachusetts Gen Hosp, Ctr Engn Med & Surg Serv, BioMEMS Resource Ctr, Shriners Hosp Children, Boston, MA 02114 USA
Harvard Univ, Sch Med, Boston, MA 02114 USA
Massachusetts Gen Hosp, Boston, MA 02129 USAMassachusetts Gen Hosp, Ctr Engn Med & Surg Serv, BioMEMS Resource Ctr, Shriners Hosp Children, Boston, MA 02114 USA